Recombinant Human Ubiquitin-Conjugating Enzyme E2M, His-tagged
Cat.No. : | UBE2M-6849H |
Product Overview : | Recombinant human UBE2M protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. |
- Specification
- Gene Information
- Related Products
Description : | UBE2M belongs to the ubiquitin-conjugating enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.2M NaCl, 1mM DTT. |
Molecular Mass : | 23.5 kDa (207aa) confirmed by MALDI-TOF |
Protein length : | 1-183aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSHMIKLFS LKQQKKEEES AGGTKGSSKK ASAAQLRIQK DINELNLPKT CDISFSDPDD LLNFKLVICP DEGFYKSGKF VFSFKVGQGY PHDPPKVKCE TMVYHPNIDL EGNVCLNILR EDWKPVLTIN SIIYGLQYLF LEPNPEDPLN KEAAEVLQNN RRLFEQNVQR SMRGGYIGST YFERCLK |
Purity : | >95% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | UBE2M ubiquitin-conjugating enzyme E2M [ Homo sapiens ] |
Official Symbol : | UBE2M |
Synonyms : | UBE2M; ubiquitin-conjugating enzyme E2M; ubiquitin conjugating enzyme E2M (homologous to yeast UBC12) , ubiquitin conjugating enzyme E2M (UBC12 homolog, yeast); NEDD8-conjugating enzyme Ubc12; hUbc12; UBC12; yeast UBC12 homolog; NEDD8 protein ligase; NEDD8 carrier protein; ubiquitin-protein ligase M; ubiquitin carrier protein M; ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast); UBC-RS2; |
Gene ID : | 9040 |
mRNA Refseq : | NM_003969 |
Protein Refseq : | NP_003960 |
MIM : | 603173 |
UniProt ID : | P61081 |
Chromosome Location : | 19q13.43 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Ubiquitin mediated proteolysis, organism-specific biosystem; |
Function : | ATP binding; NEDD8 ligase activity; acid-amino acid ligase activity; ligase activity; nucleotide binding; protein binding; ribosomal S6-glutamic acid ligase activity; ubiquitin-protein ligase activity; ubiquitin-protein ligase activity; |
Products Types
◆ Recombinant Protein | ||
UBE2M-857H | Recombinant Human UBE2M protein(Met1-Lys183) | +Inquiry |
UBE2M-4878R | Recombinant Rhesus Macaque UBE2M Protein, His (Fc)-Avi-tagged | +Inquiry |
UBE2M-6685H | Recombinant Human UBE2M Protein (Met1-Lys183), His tagged | +Inquiry |
UBE2M-05H | Recombinant Human Ubiquitin Conjugating Enzyme 12, His6-Tagged | +Inquiry |
UBE2M-5065R | Recombinant Rhesus monkey UBE2M Protein, His-tagged | +Inquiry |
◆ Lysates | ||
UBE2M-567HCL | Recombinant Human UBE2M 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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