Recombinant Human Adenosylmethionine Decarboxylase 1, His-tagged
Cat.No. : | AMD1-2483H |
Product Overview : | Recombinant human AMD1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. |
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Description : | AMD1 is synthesized initially as an inactive proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT. |
Molecular Mass : | 33.4 kDa (292aa) confirmed by MALDI-TOF |
Protein length : | 68-334aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSHMSSMFV SKRRFILKTC GTTLLLKALV PLLKLARDYS GFDSIQSFFY SRKNFMKPSH QGYPHRNFQE EIEFLNAIFP NGAAYCMGRM NSDCWYLYTL DFPESRVISQ PDQTLEILMS ELDPAVMDQF YMKDGVTAKD VTRESGIRDL IPGSVIDATM FNPCGYSMNG MKSDGTYWTI HITPEPEFSY VSFETNLSQT SYDDLIRKVV EVFKPGKFVT TLFVNQSSKC RTVLASPQKI EGFKRLDCQS AMFNDYNFVF TSFAKKQQQQ QS |
Purity : | >80% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml (determined by Bradford assay) |
Gene Name : | AMD1 adenosylmethionine decarboxylase 1 [ Homo sapiens ] |
Official Symbol : | AMD1 |
Synonyms : | AMD1; adenosylmethionine decarboxylase 1; S adenosylmethionine decarboxylase 1; S-adenosylmethionine decarboxylase proenzyme; SAMDC; S-adenosylmethionine decarboxylase 1; AMD; ADOMETDC; FLJ26964; DKFZp313L1234; |
Gene ID : | 262 |
mRNA Refseq : | NM_001033059 |
Protein Refseq : | NP_001028231 |
MIM : | 180980 |
UniProt ID : | P17707 |
Chromosome Location : | 6q21 |
Pathway : | Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Cysteine and methionine metabolism, organism-specific biosystem; Cysteine and methionine metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; |
Function : | adenosylmethionine decarboxylase activity; adenosylmethionine decarboxylase activity; lyase activity; |
Products Types
◆ Recombinant Protein | ||
AMD1-130H | Recombinant Human AMD1 Protein, His-tagged | +Inquiry |
AMD1-303R | Recombinant Rat AMD1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Amd1-591M | Recombinant Mouse Amd1 Protein, MYC/DDK-tagged | +Inquiry |
AMD1-1941C | Recombinant Chicken AMD1 | +Inquiry |
AMD1-516H | Recombinant Human AMD1 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
AMD1-8886HCL | Recombinant Human AMD1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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