Recombinant Human Tumor Necrosis Factor Receptor Superfamily, Member 1A, His-tagged

• Cat.No.: TNFRSF1A-7162H
• Product Overview: Recombinant human TNFRSF1A protein, fused to His-tag at N-terminus, was expressed in E. coli. MW: 20.8 kDa.

Specification

• Description: TNFRSF1A is a member of the tumor necrosis factor receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate the transcription factor NF-kB, mediate apoptosis, and function as a regulator of inflammation. It plays regulatory roles in the signal transduction mediated by the receptor.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 2M Urea.
• Molecular Mass: 20.8 kDa(186aa)
• Protein length: 41-201aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMDSVCP QGKYIHPQNN SICCTKCHKG TYLYNDCPGP GQDTDCRECE SGSFTASENH LRHCLSCSKC RKEMGQVEIS SCTVDRDTVC GCRKNQYRHY WSENLFQCFN CSLCLNGTVH LSCQEKQNTV CTCHAGFFLR ENECVSCSNC KKSLECTKLC LPQIEN
• Purity: >85% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1.0 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: TNFRSF1A tumor necrosis factor receptor superfamily, member 1A [ Homo sapiens ]
• Official Symbol: TNFRSF1A
• Synonyms: TNFRSF1A; tumor necrosis factor receptor superfamily, member 1A; TNFR1; tumor necrosis factor receptor superfamily member 1A; CD120a; TNF R; TNF R I; TNF R55; TNFAR; TNFR60; TNF-R1; TNF-RI; TNFR-I; tumor necrosis factor-alpha receptor; tumor necrosis factor receptor type 1; tumor necrosis factor binding protein 1; tumor necrosis factor receptor 1A isoform beta; FPF; p55; p60; TBP1; TNF-R; p55-R; TNFR55; TNF-R-I; TNF-R55; MGC19588
• Gene ID: 7132
• mRNA Refseq: NM_001065
• Protein Refseq: NP_001056
• MIM: 191190
• UniProt ID: P19438
• Chromosome Location: 12p13.2
• Pathway: Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; Apoptosis, organism-specific biosystem
• Function: protease binding; protein binding; receptor activity; tumor necrosis factor binding; tumor necrosis factor-activated receptor activity