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Recombinant Human Synaptosomal-Associated Protein, 25kDa

Cat.No. : SNAP25-6928H
Product Overview : Recombinant SNAP25 protein was expressed in E. coli and purified by using conventional chromatography techniques. MW: 23 kDa.
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  • Gene Information
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Description : SNAP25 is an essential component of the core complex that mediates presynaptic vesicle trafficking. Thus, SNAP-25 is directly involved in the release of neurotransmitters and this protein exists as two alternative isoforms, SNAP25A and SNAP25B which differ by 9 amino acids in central portion of these proteins.
Source : E. coli
Species : Human
Tag : N/A
Form : Liquid in 25mM Tris pH 7.5, 1mM DTT, 2mM EDTA, 10% glycerol
Molecular Mass : 23 kDa (206 aa), confirmed by MALDI-TOF.
Protein length : 1-206aa
AA Sequence : MAEDADMRNE LEEMQRRADQ LADESLESTR RMLQLVEESK DAGIRTLVML DEQGEQLERI EEGMDQINKD MKEAEKNLTD LGKFCGLCVC PCNKLKSSDA YKKAWGNNQD GVVASQPARV VDEREQMAIS GGFIRRVTND ARENEMDENL EQVSGIIGNL RHMALDMGNE IDTQNRQIDR IMEKADSNKT RIDEANQRAT KMLGSG
Purity : >90% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration : 1 mg/ml (determined by Bradford assay)
Gene Name : SNAP25 synaptosomal-associated protein, 25kDa [ Homo sapiens ]
Official Symbol : SNAP25
Synonyms : SNAP25; synaptosomal-associated protein, 25kDa; SNAP, synaptosomal associated protein, 25kD; synaptosomal-associated protein 25; bA416N4.2; dJ1068F16.2; resistance to inhibitors of cholinesterase 4 homolog; RIC 4; RIC4; SEC9; SNAP 25; SUP; super protein; SNAP; RIC-4; SNAP-25; FLJ23079;
Gene ID : 6616
mRNA Refseq : NM_003081
Protein Refseq : NP_003072
MIM : 600322
UniProt ID : P60880
Chromosome Location : 20p12-p11.2
Pathway : Acetylcholine Neurotransmitter Release Cycle, organism-specific biosystem; BoNT Light Chain Types A, C1, E cleave SNAP-25, organism-specific biosystem; Botulinum neurotoxicity, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Dopamine Neurotransmitter Release Cycle, organism-specific biosystem; Effects of Botulinum toxin, organism-specific biosystem;
Function : SNARE binding; myosin binding; protein N-terminus binding; protein binding; protein domain specific binding; syntaxin-1 binding; voltage-gated potassium channel activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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