Active Recombinant Mouse HDAC5, GST-tagged
Cat.No. : | HDAC5-1358M |
Product Overview : | Recombinant mouse HDAC5 (617-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | HDAC5 or Histone deacetylase 5 belongs to the class II histone deacetylase/acuc/apha family that possesses histone deacetylase activity and represses transcription when tethered to a promoter. HDAC 5 plays a critical role in transcriptional regulation, cell cycle progression, and developmental events and also acts as a potential therapeutic target for the prevention of atherosclerosis. HDAC5 can co-immunoprecipitates with HDAC3 family members forming multicomplex proteins. HDAC5 can also interact with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. HDAC5 gene is thought to be associated with colon cancer. |
Source : | Sf9 Cells |
Species : | Mouse |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 110 RLU/min/ng |
Molecular Mass : | ~80 kDa |
Protein length : | 617 aa-end |
Purity : | >90% |
Applications : | HDAC Assay, Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | Hdac5 histone deacetylase 5 [ Mus musculus ] |
Official Symbol : | HDAC5 |
Synonyms : | HDAC5; histone deacetylase 5; HD5; histone deacetylase 4; histone deacetylase mHDA1; Hdac4; mHDA1; AI426555; mKIAA0600; |
Gene ID : | 15184 |
mRNA Refseq : | NM_001077696 |
Protein Refseq : | NP_001071164 |
Pathway : | B Cell Receptor Signaling Pathway, organism-specific biosystem; Cell cycle, organism-specific biosystem; MicroRNAs in cardiomyocyte hypertrophy, organism-specific biosystem; estrogen signalling, organism-specific biosystem; |
Function : | histone deacetylase activity; hydrolase activity; protein binding; protein kinase C binding; repressing transcription factor binding; transcription corepressor activity; transcription corepressor activity; transcription factor binding; |
Products Types
◆ Recombinant Protein | ||
HDAC5-4647H | Recombinant Human HDAC5 Protein, GST-tagged | +Inquiry |
HDAC5-1876R | Recombinant Rhesus Macaque HDAC5 Protein, His (Fc)-Avi-tagged | +Inquiry |
HDAC5-164H | Recombinant Human HDAC5 Protein, His-tagged | +Inquiry |
HDAC5-312H | Active Recombinant Human HDAC5 Protein | +Inquiry |
HDAC5-48H | Recombinant Human HDAC5 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
HDAC5-5604HCL | Recombinant Human HDAC5 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1741 | HDAC5 Fluorogenic Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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