Recombinant Human ACVR2A, His-tagged
Cat.No. : | ACVR2A-6994H |
Product Overview : | Recombinant human ACVR2A (161-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag. |
- Specification
- Gene Information
- Related Products
Description : | ACVR2A encodes activin A type II receptor that are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins is an autocrine/paracrine regulator in the human placenta. ACVR2A is highly expressed in human brain and ovary. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | His |
Form : | Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. |
Molecular Mass : | ~47 kDa |
Protein length : | 161 aa-end |
Purity : | >90% |
Applications : | Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | ACVR2A activin A receptor, type IIA [ Homo sapiens ] |
Official Symbol : | ACVR2A |
Synonyms : | ACVR2A; activin A receptor, type IIA; activin A receptor, type II , ACVR2; activin receptor type-2A; ACTRII; ACVR2; |
Gene ID : | 92 |
mRNA Refseq : | NM_001616 |
Protein Refseq : | NP_001607 |
MIM : | 102581 |
UniProt ID : | P27037 |
Chromosome Location : | 2q22.2-q23.3 |
Pathway : | ALK1 signaling events, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Developmental Biology, organism-specific biosystem; Regulation of Signaling by NODAL, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by BMP, organism-specific biosystem; |
Function : | ATP binding; contributes_to activin binding; activin receptor activity, type II; contributes_to activin-activated receptor activity; coreceptor activity; growth factor binding; inhibin beta-A binding; inhibin beta-B binding; metal ion binding; nucleotide binding; protein binding; contributes_to protein binding; protein self-association; protein serine/threonine kinase activity; receptor activity; receptor signaling protein serine/threonine kinase activity; transforming growth factor beta-activated receptor activity; transmembrane receptor protein serine/threonine kinase activity; |
Products Types
◆ Recombinant Protein | ||
ACVR2A-3097HCL | Recombinant Human ACVR2A cell lysate, Myc/DDK tag | +Inquiry |
ACVR2A-292H | Recombinant Human ACVR2A Protein, His/GST-tagged | +Inquiry |
ACVR2A-150R | Recombinant Rat ACVR2A Protein, His (Fc)-Avi-tagged | +Inquiry |
ACVR2A-0786H | Recombinant Human ACVR2A Protein (P191-N487), His tagged | +Inquiry |
ACVR2A-0785H | Recombinant Human ACVR2A Protein (P191-N487), Tag Free | +Inquiry |
◆ Lysates | ||
ACVR2A-3096HCL | Recombinant Human ACVR2A cell lysate | +Inquiry |
ACVR2A-2280MCL | Recombinant Mouse ACVR2A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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