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Recombinant Human ACVR2B, GST-tagged

Cat.No. : ACVR2B-6995H
Product Overview : Recombinant human ACVR2B (182-488) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
  • Specification
  • Gene Information
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Description : ACVR2B or activin A receptor, type IIB is belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins that signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. ACVR2B is help to regulate muscle growth. ACVR2B is a transmembrane protein that composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity.
Source : Sf9 Cells
Species : Human
Tag : GST
Form : Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Molecular Mass : ~61 kDa
Protein length : 182-488 aa
Purity : >85%
Applications : Western Blot
Storage : Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
Concentration : 0.1 μg/μl
Gene Name : ACVR2B activin A receptor, type IIB [ Homo sapiens ]
Official Symbol : ACVR2B
Synonyms : ACVR2B; activin A receptor, type IIB; activin receptor type-2B; ActR IIB; HTX4; ACTRIIB; ActR-IIB;
Gene ID : 93
mRNA Refseq : NM_001106
Protein Refseq : NP_001097
MIM : 602730
UniProt ID : Q13705
Chromosome Location : 3p22
Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Developmental Biology, organism-specific biosystem; Regulation of Signaling by NODAL, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by BMP, organism-specific biosystem; Signaling by NODAL, organism-specific biosystem;
Function : ATP binding; activin binding; activin receptor activity, type II; contributes_to activin receptor activity, type II; growth factor binding; inhibin beta-A binding; inhibin beta-B binding; metal ion binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; receptor activity; receptor signaling protein serine/threonine kinase activity; transforming growth factor beta-activated receptor activity; transmembrane receptor protein serine/threonine kinase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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