Recombinant Human CDC42, GST/His-tagged
Cat.No. : | CDC42-7033H |
Product Overview : | Recombinant full-length human CDC42 was expressed in E. coli cells using a N-dual GST/His tag. |
- Specification
- Gene Information
- Related Products
Description : | CDC42 is a member of the Rho family of GTPases and is part of cellular pathways fundamental to growth, differentiation and apoptosis. Downstream targets for CDC42 include those that regulate the actin cytoskeleton (e.g. WASP) and cellular stress pathways (e.g. PAK) as well as the coatomer protein complex and PAR6. CDC42 is involved in the G(1)-S progression of the cell cycle. CDC42 and its downstream effector mDia3 are involved in bi-orientation and stabilization of spindle microtubules attachment to kinetochores and regulate chromosome alignment and segregation during mitosis. |
Source : | E. coli |
Species : | Human |
Tag : | GST/His |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~48 kDa |
Protein length : | Full length |
Purity : | >90% |
Applications : | Kinase Assay, Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.2 μg/μl |
Gene Name : | CDC42 cell division cycle 42 (GTP binding protein, 25kDa) [ Homo sapiens ] |
Official Symbol : | CDC42 |
Synonyms : | CDC42; cell division cycle 42 (GTP binding protein, 25kDa); cell division cycle 42 (GTP binding protein, 25kD); cell division control protein 42 homolog; CDC42Hs; G25K; G25K GTP-binding protein; GTP-binding protein, 25kD; growth-regulating protein; small GTP binding protein CDC42; dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)); dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)); |
Gene ID : | 998 |
mRNA Refseq : | NM_001039802 |
Protein Refseq : | NP_001034891 |
MIM : | 116952 |
UniProt ID : | P60953 |
Chromosome Location : | 1p36.1 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem; Axon guidance, organism-specific biosystem; |
Function : | GTP binding; GTP-dependent protein binding; GTPase activity; GTPase activity; mitogen-activated protein kinase kinase kinase binding; nucleotide binding; protein binding; thioesterase binding; |
Products Types
◆ Recombinant Protein | ||
CDC42-935R | Recombinant Rat CDC42 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDC42-1806H | Recombinant Human CDC42 protein(Met1-Cys188), GST-tagged | +Inquiry |
CDC42-0936H | Recombinant Human CDC42 Protein, GST-pstS1-Tagged | +Inquiry |
CDC42-143C | Recombinant Cynomolgus Monkey CDC42 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDC42-0934H | Recombinant Human CDC42 Protein, GST-Tagged | +Inquiry |
◆ Lysates | ||
CDC42-7655HCL | Recombinant Human CDC42 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-0190 | Cdc42 G-LISA Activation Assay Kit (Colorimetric) | +Inquiry |
Kit-0191 | Cdc42 G-LISA Activation Assay Kit (Colorimetric) II | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionCDC42 controls cytoskeletal dynamics, leading to changes in cell shape and movement.
CDC42 is important in neuronal development and plays a role in forming and remodeling synaptic connections.
Changes in CDC42 activity can impact aging processes and contribute to the development of age-related diseases.
CDC42 facilitates cancer progression by enhancing cell migration, invasion, and metastatic potential.
CDC42 aids in wound healing and regeneration by guiding cell migration and tissue restructuring.
CDC42 is crucial for cell division and cycle progression, coordinating cellular events for proper division.
CDC42 regulates immune cell movement and activation, essential for immune response and surveillance.
Customer Reviews (3)
Write a reviewReliable protein crystallography, essential for structural studies.
Exceptional protein engineering services, meets our lab's needs.
Efficient peptide synthesis, crucial for our peptide research.
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