Recombinant Human CLEC2B, His-tagged

• Cat.No.: CLEC2B-7120H
• Product Overview: Recombinant human CLEC2B protein, fused to His-tag at N-terminus, was expressed in E.coli.

Specification

• Description: CLEC2B is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The type 2 transmembrane protein may function as a cell activation antigen. An alternative splice variant has been described but its full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2M UREA, 10% glycerol
• Molecular Mass: 16.9kDa (147aa)
• Protein length: 26-149aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSKLTRDSQ SLCPYDWIGF QNKCYYFSKE EGDWNSSKYN CSTQHADLTI IDNIEEMNFL RRYKCSSDHWIGLKMAKNRT GQWVDGATFT KSFGMRGSEG CAYLSDDGAA TARCYTERKW ICRKRIH
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml

Gene Information

• Gene Name: CLEC2B C-type lectin domain family 2, member B [ Homo sapiens ]
• Official Symbol: CLEC2B
• Synonyms: CLEC2B; C-type lectin domain family 2, member B; C type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 2 (activation induced) , CLECSF2; C-type lectin domain family 2 member B; AICL; HP10085; activation-induced C-type lectin; C-type lectin superfamily member 2; IFN-alpha2b-inducing related protein 1; IFN-alpha-2b-inducing-related protein 1; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 2 (activation-induced); IFNRG1; CLECSF2
• Gene ID: 9976
• mRNA Refseq: NM_005127
• Protein Refseq: NP_005118
• MIM: 603242
• UniProt ID: Q92478
• Chromosome Location: 12p13-p12
• Function: binding; sugar binding