Recombinant Human Ezrin, His-tagged
Cat.No. : | EZR-516H |
Product Overview : | Recombinant Human Ezrin,encoding the mature form of human EZR(Pro2-Leu586) was expressed with a his tag at the N-terminus. |
- Specification
- Gene Information
- Related Products
Cat. No. : | EZR-516H |
Description : | The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. |
Source : | E. coli |
Molecular Mass : | The recombinant human EZR consists of 601 amino acids and predicts a molecular mass of 71.2 KDa. It migrates as an approximately 82 KDa band in SDS-PAGE under reducing conditions. |
Predicted N terminal : | His |
Formulation : | Lyophilized from a 0.2μm filtered solution of PBS 100mM Arg 10% glycerol, 0.1%Twen 20, pH 7.5. |
Purity : | Greater than 60% as determined by SDS-PAGE |
Stability : | Store it under sterile conditions at -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Gene Name : | EZR ezrin [ Homo sapiens ] |
Official Symbol : | EZR |
Synonyms : | EZR; ezrin; VIL2, villin 2 (ezrin); cytovillin 2 CVL; CVIL; ezrin; p81; villin-2; cytovillin 2 |
Gene ID : | 7430 |
mRNA Refseq : | NM_001111077 |
Protein Refseq : | NP_001104547 |
MIM : | 123900 |
UniProt ID : | P15311 |
Chromosome Location : | 6q25.3 |
Pathway : | Axon guidance; Developmental Biology; Gastric acid secretion |
Function : | actin filament binding; cell adhesion molecule binding ; protein binding |
Products Types
◆ Recombinant Protein | ||
Ezrin-30148H | Recombinant Human Ezrin protein, GST-tagged | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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