Rabbit polyclonal to human DUOX2.
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.
Synthetic peptide corresponding to internal sequence amino acids of Human DUOX2.
Reacts with Rat, Human; Predicted to work withMouse
Immunogen affinity purified
HeLa, Jurkat, MCF7 and SMMC cell lysates.
In the N-terminal section; belongs to the peroxidase family.Contains 3 EF-hand domains.Contains 1 FAD-binding FR-type domain.Contains 1 ferric oxidoreductase domain.
100 µg at 0.5mg/ml
Preservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azideConstituents: 0.1% Dibasic monohydrogen sodium phosphate, 0.45% Sodium chloride, 2.5% BSA
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
|Function||NAD(P)H oxidase activity; calcium ion binding; heme binding; peroxidase activity|