Recombinant Human DEDD, His-tagged
Cat.No. : | DEDD-7245H |
- Specification
- Gene Information
- Related Products
product overview : | Recombinant human DEDD protein, fused to His-tag at N-terminus, was expressed in E.coli. |
description : | Death effector domain-containing protein, also known as DEDD, is a cytoplasmic protein. It translocates to the nucleus during CD95-mediated apoptosis, where it localizes to nucleoli-like structures, activates caspase-6 and specifically inhibits RNA polymerase I-dependent transcription. The cell death activity of DEDD relates to its nuclear localization. DEDD is widely expressed in a variety of tissues, with highest levels in the testis. Overexpression of this gene was shown to induce weak apoptosis. |
source : | E. coli |
species : | Human |
tag : | His |
form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol |
molecular mass : | 38.9 kDa (338aa) |
protein length : | 1-318aa |
aa sequence : | MGSSHHHHHH SSGLVPRGSH MAGLKRRASQ VWPEEHGEQE HGLYSLHRMF DIVGTHLTHR DVRVLSFLFV DVIDDHERGL IRNGRDFLLALERQGRCDES NFRQVLQLLR IITRHDLLPY VTLKRRRAVC PDLVDKYLEE TSIRYVTPRA LSDPEPRPPQ PSKTVPPHYP VVCCPTSGPQ MCSKRPARGR ATLGSQRKRR KSVTPDPKEK QTCDIRLRVR AEYCQHETAL QGNVFSNKQD PLERQFERFN QANTILKSRD LGSIICDIKFSELTYLDAFW RDYINGSLLE ALKGVFITDS LKQAVGHEAI KLLVNVDEED YELGRQKLLR NLMLQALP |
purity : | >85% by SDS - PAGE |
applications : | SDS-PAGE |
storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
concentration : | 0.5 mg/ml |
gene name : | DEDD death effector domain containing [ Homo sapiens ] |
official symbol : | DEDD |
synonyms : | DEDD; death effector domain containing; death effector domain-containing protein; CASP8IP1; DEDD1; DEFT; FLDED1; KE05; DEDPro1; FLDED-1; death effector domain-containing testicular molecule; |
Gene ID : | 9191 |
mrna refseq : | NM_001039711 |
protein refseq : | NP_001034800 |
mim : | 606841 |
uniprot id : | O75618 |
chromosome location : | 1q23.1 |
function : | DNA binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
DEDD-1050R | Recombinant Rhesus Macaque DEDD Protein, His (Fc)-Avi-tagged | +Inquiry |
DEDD-1485R | Recombinant Rat DEDD Protein, His (Fc)-Avi-tagged | +Inquiry |
DEDD-2513H | Recombinant Human DEDD Protein, GST-tagged | +Inquiry |
DEDD-539H | Recombinant Human DEDD Protein, His-tagged | +Inquiry |
DEDD-750Z | Recombinant Zebrafish DEDD | +Inquiry |
◆ Lysates | ||
DEDD-6995HCL | Recombinant Human DEDD 293 Cell Lysate | +Inquiry |
DEDD-6996HCL | Recombinant Human DEDD 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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