Recombinant Human CTSS, His-tagged
Cat.No. : | CTSS-7251H |
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- Gene Information
- Related Products
product overview : | Recombinant human CTSS protein, fused to His-tag at N-terminus, was expressed in E.coli. |
description : | Cathepsin S, also known as CTSS, is a member of the peptidase C1 family. This protein is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. CTSS can function as an elastase over a broad pH range in alveolar macrophages. |
source : | E. coli |
species : | Human |
tag : | His |
form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol |
molecular mass : | 38.1 kDa (336aa) |
protein length : | 17-331aa |
aa sequence : | MGSSHHHHHH SSGLVPRGSH MQLHKDPTLD HHWHLWKKTY GKQYKEKNEE AVRRLIWEKN LKFVMLHNLE HSMGMHSYDL GMNHLGDMTS EEVMSLMSSL RVPSQWQRNI TYKSNPNWIL PDSVDWREKG CVTEVKYQGS CGACWAFSAV GALEAQLKLK TGKLVSLSAQ NLVDCSTEKY GNKGCNGGFM TTAFQYIIDN KGIDSDASYP YKAMDQKCQY DSKYRAATCS KYTELPYGRE DVLKEAVANK GPVSVGVDAR HPSFFLYRSG VYYEPSCTQN VNHGVLVVGY GDLNGKEYWL VKNSWGHNFG EEGYIRMARN KGNHCGIASF PSYPEI |
purity : | >85% by SDS - PAGE |
applications : | SDS-PAGE |
storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
concentration : | 1 mg/ml |
gene name : | CTSS cathepsin S [ Homo sapiens ] |
official symbol : | CTSS |
synonyms : | CTSS; cathepsin S; MGC3886; FLJ50259; |
Gene ID : | 1520 |
mrna refseq : | NM_001199739 |
protein refseq : | NP_001186668 |
mim : | 116845 |
uniprot id : | P25774 |
chromosome location : | 1q21 |
pathway : | Adaptive Immune System, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Antigen processing-Cross presentation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Endosomal/Vacuolar pathway, organism-specific biosystem; |
function : | cysteine-type endopeptidase activity; peptidase activity; |
Products Types
◆ Recombinant Protein | ||
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CTSS-2118H | Recombinant Human CTSS Protein, GST-tagged | +Inquiry |
Ctss-1293R | Recombinant Rat Ctss Protein, His-tagged | +Inquiry |
CTSS-282H | Active Recombinant Human CTSS protein(Met1-Ile331), His-tagged | +Inquiry |
CTSS-911M | Active Recombinant Mouse CTSS Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
CTSS-27405TH | Native Human CTSS | +Inquiry |
◆ Lysates | ||
CTSS-1563MCL | Recombinant Mouse CTSS cell lysate | +Inquiry |
CTSS-3021HCL | Recombinant Human CTSS cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-2353 | Cathepsin S Inhibitor Screening Kit (Fluorometric) | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe function of CTSS proteins can be studied through gene knockout or knockdown techniques, such as using techniques such as CRISPR-Cas9 or RNAi. These techniques can create cellular models of missing or reduced CTSS proteins to observe their effects on cell death, among other things.
Expression level of CTSS protein can be detected by immunohistochemistry, western blotting, and real-time quantitative PCR.
CTSS proteins promote cell death by degrading proteins inside cells. During apoptosis, CTSS proteins degrade key proteins within cells, leading to cell death.
The interaction between CTSS proteins and other proteins is regulated by the formation of complexes or the regulation of signal transduction pathways. These interactions can be influenced by a variety of factors, such as ion concentrations, neurotransmitters, and growth factors.
Some studies have shown that the expression level of CTSS protein may be associated with the onset and progression of certain diseases. For example, in some cancers, the expression level of the CTSS protein may change.
It is mainly expressed in lysosomes, which is one of the major proteases in lysosomes.
Customer Reviews (3)
Write a reviewHigh catalytic efficiency, short time, saving time.
The solubility is very good and can be easily dissolved in various buffers.
Anti-pollution ability is very strong, not easy to be polluted.
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