Recombinant Human CD226, His-tagged

• Cat.No.: CD226-7254H

Specification

• product overview: Recombinant human CD226 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• description: CD226 is a 65kDa glycoprotein expressed on the surface NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. This protein also plays a role in megakaryocytic cell maturation
• source: E. coli
• species: Human
• tag: His
• form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol
• molecular mass: 29.4 kDa (259aa)
• protein length: 19-254aa
• aa sequence: MGSSHHHHHH SSGLVPRGSH MGSEEVLWHT SVPFAENMSL ECVYPSMGIL TQVEWFKIGT QQDSIAIFSP THGMVIRKPY AERVYFLNSTMASNNMTLFF RNASEDDVGY YSCSLYTYPQ GTWQKVIQVV QSDSFEAAVP SNSHIVSEPG KNVTLTCQPQ MTWPVQAVRW EKIQPRQIDL LTYCNLVHGR NFTSKFPRQI VSNCSHGRWS VIVIPDVTVS DSGLYRCYLQ ASAGENETFV MRLTVAEGKT DNQYTLFVA
• purity: >90% by SDS - PAGE
• applications: SDS-PAGE
• storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• concentration: 1 mg/ml

Gene Information

• gene name: CD226 CD226 molecule [ Homo sapiens ]
• official symbol: CD226
• synonyms: CD226; CD226 molecule; CD226 antigen; DNAM 1; DNAM1; PTA1; TLiSA1; adhesion glycoprotein; DNAX accessory molecule 1; DNAX accessory molecule-1; platelet and T cell activation antigen 1; T lineage-specific activation antigen 1 antigen; DNAM-1
• Gene ID: 10666
• mrna refseq: NM_006566
• protein refseq: NP_006557
• mim: 605397
• uniprot id: Q15762
• chromosome location: 18q22.3
• pathway: Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem
• function: cell adhesion molecule binding; integrin binding; protein binding; protein kinase binding; receptor activity