Address: 45-1 Ramsey Road, Shirley, NY 11967, USA    USA: 1-631-559-9269  1-631-448-7888   Fax: 1-631-938-8127  Europe: 44-207-048-3343   Email: info@creative-biomart.com
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Recombinant Human CD-7

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Fc(1)
His(3)
Cat. No.:
CDA079P
Product Overview:
Recombinant Human full length CD-7 protein expressed in E.coli,66 kDa.
Description:
CD7 (gp40, Leu9) is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxy-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on maligant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3"-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylat
Synonyms:
CD7; GP40; LEU-9; TP41; Tp40; GP40; LEU-9; Leu-9; CD7 antigen; CD7 antigen (p41); CD7 molecule; T-cell antigen CD7; T-cell leukemia antigen; p41 protein.
Source:
E.coli.
Presentation:
Recombinant Human CD-7 protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Applications:
•ELISA•Inhibition Assays •Western Blotting
Characterization:
On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 66 kDa.
Storage:
Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months.


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Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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