Catalog # or name ...
Hamster Anti-EMR3 Monoclonal Antibody
This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses.
Recognizes human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 (EMR3), which is a 56 kDa member of the EGF-7 transmembrane (TM7) family of adhesion receptors. EMR3 is expressed at the cell surface as a heterodimer.
ARHO-EMR3-CD97 (EGF1) transfectants
>90 % pure (SDS-PAGE). Protein A chromatography
Lot specificLot specific
PBS, pH 7.4
Short term store at 2-8°C. Long term, aliquot and store at -20°C. Prepare working dilution only prior to immediate use. Avoid multiple freeze/thaw cycles. Should this product contain a precipitate, we recommend microcentrifugation before use.
0.09 % Sodium azide
This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1–1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Antigen Gene Information
EMR3 egf-like module containing, mucin-like, hormone receptor-like 3 [ Homo sapiens ]
EMR3; egf-like module containing, mucin-like, hormone receptor-like 3; EGF-like module-containing mucin-like hormone receptor-like 3; EGF-like module receptor 3; egf-like module-containing mucin-like receptor 3;
Class B/2 (Secretin family receptors), organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Other, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by GPCR, organism-specific biosystem;
G-protein coupled receptor activity; calcium ion binding; receptor activity; signal transducer activity;
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