Catalog # or name ...
Rat Anti-Itgal Monoclonal Antibody
Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), also known as ITGAL, is a human gene which functions in the immune system. It is involved in cellular adhesion and costimulatory signaling. It is the target of the drug efalizumab.
Anti-Mouse CD11a recognizes the alpha subunit of the mouse leukocyte function associated antigen-1 (LFA-1). CD11a/CD18alpha1 beta2 leukocyte integrin is a member of a family of heterodimeric receptors which mediate cellular adhesion reactions. The CD11a LFA-1 antigen is present on >97% thymocytes, >95% blood lymphocytes, 79% bone marrow cells and certain lymphoma and macrophage-like cell lines.
0.5mg/ml (OD280nm)0.5mg/ml (OD280nm)
0.01M PBS, pH 7.4 containing 1% BSA
Store at 2-8°C. DO NOT FREEZE.
0.09% Sodium azide
This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 – 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Antigen Gene Information
Itgal integrin alpha L [ Mus musculus ]
ITGAL; integrin alpha L; integrin alpha-L; alpha L integrin; lymphocyte antigen 15; CD11 antigen-like family member A; leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; lymphocyte function associated antigen 1, alpha polypeptide; Cd11a; LFA-1; Ly-15; Ly-21; (p180); LFA-1A;
Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Focal Adhesion, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem;
cell adhesion molecule binding; protein complex binding; protein heterodimerization activity; receptor activity;
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