Recombinant Human AIP, His-tagged

• Cat.No.: AIP-3595H
• Product Overview: Recombinant human AIP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques (1-330 aa).

Specification

• Cat. No.: AIP-3595H
• Description: Aryl hydrocarbon receptor (AHR) interacting protein, also known as AIP, may play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting. It is a Cellular negative regulator of the hepatitis B virus (HBV) X protein. Also, AIP is a ubiquitously expressed protein, binds to HSP 90 and AHR through a highly conserved carboxy-terminal tetraticopeptide repeat domain.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
• Molecular Weight: 39.8 kDa (350aa), confirmed by MALDI-TOF
• Purity: > 90% by SDS - PAGE
• Concentration: 1 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MADIIARLRE DGIQKRVIQE GRGELPDFQD GTKATFHYRT LHSDDEGTVL DDSRARGKPM ELIIGKKFKL PVWETIVCTM REGEIAQFLC DIKHVVLYPL VAKSLRNIAV GKDPLEGQRH CCGVAQMREH SSLGHADLDA LQQNPQPLIF HMEMLKVESP GTYQQDPWAM TDEEKAKAVP LIHQEGNRLY REGHVKEAAA KYYDAIACLK NLQMKEQPGS PEWIQLDKQI TPLLLNYCQC KLVVEEYYEV LDHCSSILNK YDDNVKAYFK RGKAHAAVWN AQEAQADFAK VLELDPALAP VVSRELRALE ARIRQKDEED KARFRGIFSH
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: AIP aryl hydrocarbon receptor interacting protein [ Homo sapiens ]
• Official Symbol: AIP
• Synonyms: AIP; ARA9; XAP2; FKBP16; FKBP37; SMTPHN; aryl hydrocarbon receptor interacting protein; XAP-2; AH receptor-interacting protein; OTTHUMP00000236411; OTTHUMP00000236412; HBV-X associated protein; immunophilin homolog ARA9; HBV X-associated protein 2; aryl hydrocarbon receptor-interacting protein; aryl-hydrocarbon receptor interacting protein; aryl-hydrocarbon receptor-interacting protein; Aryl-hydrocarbon receptor-interacting protein; Immunophilin homolog ARA9
• Gene ID: 9049
• mRNA Refseq: NM_003977
• Protein Refseq: NP_003968
• MIM: 605555
• UniProt ID: O00170
• Chromosome Location: 11q13.3
• Function: protein binding; signal transducer activity; transcription coactivator activity; transcription factor binding; unfolded protein binding