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Recombinant Human CBX1, His-tagged

Cat.No. : CBX1-3580H
Product Overview : Recombinant human CBX1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques (1-185 aa).
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  • Gene Information
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Cat. No. : CBX1-3580H
Description : CBX1 is a member of the heterochromatin protein family and enriched in the heterochromatin and associated with centromeres. It is recognizes and binds histone H3 tails methylated at "Lys-9", leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. This protein may play an important role in the epigenetic control of chromatin structure and gene expression.
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 2mM DTT, 0.1M NaCl.
Molecular Weight : 23.6 kDa (205aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Purity : > 85 % by SDS - PAGE
Concentration : 1 mg/ml (determined by Bradford assay)
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MGKKQNKKKV EEVLEEEEEE YVVEKVLDRR VVKGKVEYLL KWKGFSDEDN TWEPEENLDC PDLIAEFLQS QKTAHETDKS EGGKRKADSD SEDKGEESKP KKKKEESEKP RGFARGLEPE RIIGATDSSG ELMFLMKWKN SDEADLVPAK EANVKCPQVV ISFYEERLTW HSYPSEDDDK KDDKN
Storage : Can be stored at +4℃ short term (1-2 weeks). For long term storage, aliquot and store at -20℃ or -70℃. Avoid repeated freezing and thawing cycles.
Gene Name : CBX1 chromobox homolog 1 [ Homo sapiens ]
Official Symbol : CBX1
Synonyms : CBX1; CBX; M31; MOD1; p25beta; HP1-BETA; HP1Hsbeta; HP1Hs-beta; chromobox homolog 1; chromobox protein homolog 1; HP1 beta homolog; OTTHUMP00000197313; OTTHUMP00000197314; OTTHUMP00000197316; modifier 1 protein; heterochromatin protein 1-beta; heterochromatin protein p25 beta; heterochromatin protein 1 homolog beta; chromobox homolog 1 (HP1 beta homolog Drosophila ); chromobox homolog 1 (Drosophila HP1 beta); HP1 beta homolog (Drosophila); Chromobox protein homolog 1; Heterochromatin protein 1 homolog beta; HP1 beta; Heterochromatin protein p25; Modifier 1 protein; OTTHUMP00000197315
Gene ID : 10951
mRNA Refseq : NM_001127228
Protein Refseq : NP_001120700
MIM : 604511
UniProt ID : P83916
Chromosome Location : 17q21.32
Function : chromatin binding; enzyme binding; protein binding; transcription repressor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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