Recombinant Human HMGB2 protein, His-tagged

• Cat.No.: HMGB2-3598H
• Product Overview: Recombinant Human HMGB2(1-209aa) fused with His tag at N-terminal was expressed in Insect cells.

Specification

• Source: Insect cells
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl.
• Molecular Mass: 26.4 kDa (232aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH TGSKARYDREMKN YVPPKGDKKG KKKDPNAPKR PPSAFFLFCS EHRPKIKSEH PGLSIGDTAK KLGEMWSEQS AKDKQPYEQK AAKLKEKYEK
  MGKGDPN KPRGKMSSYA FFVQTCREEH KKKHPDSSVN FAEFSKKCSE RWKTMSAKEK SKFEDMAKSDDIAAYRAKGK SEAGKKGPGR PTGSKKKNEP EDEEEEEEEE DEDEEEEDED EE
• Purity: > 90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: HMGB2 high mobility group box 2 [ Homo sapiens ]
• Official Symbol: HMGB2
• Synonyms: HMGB2; high mobility group box 2; high mobility group (nonhistone chromosomal) protein 2 , high mobility group box 2 , HMG2; high mobility group protein B2; HMG-2; high-mobility group box 2; high mobility group protein 2; high-mobility group (nonhistone chromosomal) protein 2; HMG2
• Gene ID: 3148
• mRNA Refseq: NM_002129
• Protein Refseq: NP_002120
• MIM: 163906
• UniProt ID: P26583
• Chromosome Location: 4q31
• Pathway: Activation of DNA fragmentation factor, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis induced DNA fragmentation, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem
• Function: DNA binding; DNA binding, bending; RAGE receptor binding; chemoattractant activity; damaged DNA binding; double-stranded DNA binding; protein binding; protein domain specific binding; sequence-specific DNA binding transcription factor activity; single-stranded DNA binding; transcription regulatory region DNA binding