Recombinant Human TFF1, His-tagged

• Cat.No.: TFF1-3568H
• Product Overview: Recombinant human TFF1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques(25-84aa).

Specification

• Cat. No.: TFF1-3568H
• Description: TFF1 (Trefoil factor 1) is member of trefoil family, characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. TFF1 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 100mM NaCl, 0.1mM PMSF
• Molecular Mass: 9.0 kDa (81aa), confirmed by MALDI-TOF
• Purity: > 90 % by SDS-PAGE
• Concentration: 0.5 mg/ml (determined by Bradford assay )
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MEAQTETCTV APRERQNCGF PGVTPSQCAN KGCCFDDTVR GVPWCFYPNT IDVPPEEECE F
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: TFF1 trefoil factor 1 [ Homo sapiens ]
• Official Symbol: TFF1
• Synonyms: TFF1; BCEI; D21S21; HP1.A; HPS2; pNR-2; pS2; trefoil factor 1; gastrointestinal trefoil protein pS2; breast cancer estrogen-inducible sequence; Breast cancer estrogen-inducible protein; breast cancer, estrogen-inducible sequence expressed in gastrointestinal trefoil protein pS2; pS2 protein; trefoil factor, BCE1, human pS2 induced by estrogen from human breast cancer cell line M
• Gene ID: 7031
• mRNA Refseq: NM_003225
• Protein Refseq: NP_003216
• MIM: 113710
• UniProt ID: P04155
• Chromosome Location: 21q22.3
• Function: growth factor activity