Catalog # or name ...
Mouse Anti-PNP Monoclonal Antibody
PNP belongs to the PNP/MTAP phosphorylase family of proteins. This protein catalyzes the reversible phosphorolysis of ribonucleosides and 2’-deoxyribonucleosides with specificity for guanine, hypoxanthine and their analogs. PNP deficiency is a rare autosomal recessive genetic disease associated with a severe defect in T-lymphocyte function and neurologic disorder in children, comprising four percent of combined immunodeficiency cases.
Anti-PNP recognize PNP expression in HEK293 whole cell lysate.
Purified mouse monoclonal antibody generated using E.coli expressed recombinant protein PNP (full length) as immunogen.
Each vial contains 100 µg IgG in 100 µl of citrate-tris-HCl buffer pH7.0 with 0.02% Proclin 300.
The antibody may be stored at -20°C for one year in its original formulation. Additionally, antibody may be stored at 2°C to 8°C for up to 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles of the diluted antibody.
Antigen Gene Information
PNP purine nucleoside phosphorylase [ Homo sapiens ]
PNP; purine nucleoside phosphorylase; NP, nucleoside phosphorylase; PUNP; inosine phosphorylase; purine-nucleoside:orthophosphate ribosyltransferase; NP; PRO1837; FLJ94043; FLJ97288; FLJ97312; MGC117396; MGC125915; MGC125916;
Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; Nicotinate and nicotinamide metabolism, organism-specific biosystem; Nicotinate and nicotinamide metabolism, conserved biosystem; Purine catabolism, organism-specific biosystem; Purine metabolism, organism-specific biosystem;
drug binding; nucleoside binding; phosphate ion binding; purine base binding; purine-nucleoside phosphorylase activity; purine-nucleoside phosphorylase activity;
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