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Active Recombinant Mouse Epo protein, His-tagged

Cat.No. : Epo-7421M
Product Overview : Recombinant Mouse Epo protein(P07321)(Met1-Arg192), fused with His tag, was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Mouse
Tag : His
Form : Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Bio-activity : 1. Measured by its ability to bind biotinylated human EPOR-His in a functional ELISA.2. Measured by its ability to bind mouse EPOR-Fch in a functional ELISA.3. Measured by its ability to bind human EPOR & CD131-Fc in a functional ELISA.4. Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 2-10 ng/mL.
Molecular Mass : The recombinant mouse EPO comprises 177 amino acids and has a predicted molecular mass of 20 kDa. The apparent molecular mass of the protein is approximately 37 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Protein Length : Met1-Arg192
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 96 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : Epo erythropoietin [ Mus musculus ]
Official Symbol : Epo
Synonyms : EPO; erythropoietin;
Gene ID : 13856
mRNA Refseq : NM_007942
Protein Refseq : NP_031968

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the relationship between EPO protein and cardiovascular disease? 08/05/2019

EPO protein can promote the renewal and repair of heart blood vessels, and has the effect of protecting the heart from ischemia-reperfusion damage.

How does EPO protein regulate erythropoiesis? 07/12/2019

By binding to receptors, EPO proteins activate signaling pathways that promote the proliferation and differentiation of hematopoietic stem cells in bone marrow into erythrocytes.

How about the clinical use of EPO protein? 06/12/2019

EPO protein can be used by injection or oral, and the specific method and dosage need to be determined according to the condition and the doctor's advice.

What are the implications of EPO protein research for the future of treating anemia? 05/14/2019

The study of EPO protein helps to understand the regulatory mechanism of erythropoiesis and provides new ideas and methods for the treatment of anemia, such as developing more effective EPO protein analogues or improving existing treatment regimens.

How is EPO protein treated for anemia? 05/02/2019

This protein stimulates the bone marrow to produce more red blood cells, thereby increasing hemoglobin levels and treating anemia.

What is the role of EPO protein in kidney disease? 04/04/2019

In kidney disease, due to impaired kidney function, the production of EPO protein decreases, leading to anemia. Supplementation with exogenous EPO protein can help correct anemia caused by kidney problems.

Customer Reviews (3)

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Reviews
12/28/2021

    Stability is truly remarkable, can maintain its activity even under extreme conditions.

    08/31/2021

      Can catalyze reactions even under extreme conditions.

      02/03/2019

        This protein's repeatability is truly exceptional, consistently delivering reliable results even under challenging conditions.

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