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Anti-Human TRAIL MAb Stable Cell Line-CHO

Cat.No. : CSC-P0164

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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What is the therapeutic potential of TNFSF10 protein? 11/21/2021

TNFSF10 protein holds great therapeutic potential as a target for various diseases. Studies have shown that utilizing its apoptosis-inducing ability, novel treatment strategies can be developed for cancer. Furthermore, TNFSF10 protein can be utilized in the design of immunotherapies to enhance immune responses. However, further research is needed to optimize TNFSF10 therapeutic strategies and gain a deeper understanding of its specific mechanisms in disease development.

What is the cellular source of TNFSF10 protein? 01/07/2019

The cellular source of TNFSF10 protein is diverse, including tumor cells, lymphocytes, monocytes, and dendritic cells. Additionally, some epithelial cells and endothelial cells also express TNFSF10 protein.

What is the physiological function of TNFSF10 protein in tissue remodeling? 03/07/2018

TNFSF10 protein has diverse physiological functions in tissue remodeling. It promotes inflammation, angiogenesis, and fibrosis processes. Moreover, TNFSF10 protein is involved in immune regulation and tissue repair, playing a crucial role in maintaining normal tissue functionality and structure.

What cellular processes are modulated by TNFSF10? 01/24/2018

TNFSF10 modulates multiple cellular processes beyond apoptosis induction. It can activate various signaling pathways, including the NF-κB pathway, which plays a key role in immune and inflammatory responses. TNFSF10 also regulates cell migration and invasion properties, affecting metastasis in some cancer types. Furthermore, TNFSF10 can promote immune cell activation and cytokine production, contributing to the regulation of the immune system.

What is the role of TNFSF10 protein in cancer progression and metastasis? 10/27/2017

TNFSF10 protein plays a significant role in cancer progression and metastasis. It induces apoptosis in tumor cells, inhibits tumor growth and metastasis, and regulates immune responses. Moreover, TNFSF10 protein interacts with other signaling pathways, participating in the modulation of the tumor microenvironment.

What are the transcriptional regulatory mechanisms of TNFSF10 protein? 10/23/2017

The transcriptional regulation of TNFSF10 gene involves various factors. Known regulators include transcription factors NF-κB, STAT3, and DNA methylation status. These factors modulate the expression levels of TNFSF10 gene, thereby influencing the production of TNFSF10 protein.

What are the substrate interactions of TNFSF10 protein? 04/23/2016

TNFSF10 protein interacts with its receptor, death receptor 5 (DR5), and triggers apoptosis pathway to induce cell death. Additionally, TNFSF10 protein also interacts with other ligands and receptors, such as TRAIL-R1 and TRAIL-R2, thereby regulating cell survival and death signaling transduction.

Customer Reviews (3)

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09/19/2021

    Its quality exceeding imagination, this experimental reagent becomes an indispensable tool for my experiments.

    04/07/2020

      Through its employment, I am able to delve deeper into the essence of experimental principles and phenomena.

      07/21/2017

        The exceptional performance of this experimental reagent significantly enhances the visibility of my research and amplifies my scholarly impact.

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