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Cat.No.
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CAB-4543MH
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Product Overview
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Mouse Anti-RTKN Monoclonal Antibody
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Antigen Description
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This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP.
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Target
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RTKN
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Immunogen
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RTKN (NP_149035, 451 a.a. - 550 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Host
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Mouse
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Isotype
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IgG1 Kappa
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Species
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Human
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Clone
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MAAG1990
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conjugation
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N/A
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Applications
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ELISA,WB,IHC
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Format
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Clear, colorless solution in phosphate buffered saline, pH 7.2.
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Storage
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Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Antigen Gene Information
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Gene Name
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RTKN rhotekin [ Homo sapiens ]
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Official Symbol
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RTKN
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Synonyms
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RTKN; rhotekin; B5;
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GeneID
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6242
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mRNA Refseq
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NM_001015055
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Protein Refseq
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NP_001015055
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MIM
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602288
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UniProt ID
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Q9BST9
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Chromosome Location
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2p13.1
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Pathway
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Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; G13 Signaling Pathway, organism-specific biosystem;
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Function
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GTP binding; GTP-Rho binding; GTPase inhibitor activity; nucleotide binding; protein binding;
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Download Datasheet:
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