Address: 45-1 Ramsey Road, Shirley, NY 11967, USA    USA: 1-631-559-9269  1-631-448-7888   Fax: 1-631-938-8127  Europe: 44-207-048-3343   Email: info@creative-biomart.com
Home > Products > Antibody > Monoclonal Antibodies > Mouse Anti-TNFRSF6B Monoclonal Antibody

Mouse Anti-TNFRSF6B Monoclonal Antibody

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By Species
Human(14)
By Tag
Fc(5)
His(2)
N/A(1)
Cat.No.:
DMABT-H18387
Product Overview:
Mouse Anti-TNFRSF6B Monoclonal Antibody
Antigen Description:
The DcR3 protein is a soluble member of the TNF receptor superfamily containing four TNF receptor domains with an approximate molecular weight of 35 kD. DcR3, also known as Decoy receptor 3, TR6, M68, can be secreted by monocytes and myeloid-derived dendritic cells following exposure to bacterial antigens. DcR3 is overexpressed in tumors including lung and colon cancers, gliomas, and pancreatic cancers and can be detected in the serum of cancer patients. DcR3 can also be found in the cytoplasm and endoplasmic reticulum in some cell types. This protein competes for ligand binding with cell surface receptor and can inhibit their signaling. DcR3 has been shown to bind the ligands FasL, LIGHT, and TNF like molecule2(TL1A) to inhibit binding to the cell surface receptors Fas, HVEM and LT-beta R, and death receptor4(DR3), respectively.
Target:
TNFRSF6B
Immunogen:
Human DcR3 Fc protein
Host:
Mouse
Isotype:
IgG1, kappa
species:
Human
Clone:
C09-46
Conjugation:
N/A
Applications:
WB,IP,IHC,ELISA
Preparation:
The antibody was purified by affinity chromatography.
Usage recommendation:
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤1.0 μg per 106cells in 100 μl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Concentration:
0.5 mg/ml
Storage:
The antibody solution should be stored undiluted at 4 °C.
Size:
100 μg


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Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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