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Mouse Anti-Human IRAK1 Monoclonal Antibody, MAAG3173

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Cat.No.

CAB-5726MH

Product Overview

Mouse Anti-IRAK1 Monoclonal Antibody

Antigen Description

This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target

IRAK1

Immunogen

IRAK1 (AAH54000, 530 a.a~693 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Host

Mouse

Isotype

IgG2a Kappa

Species

Human

Clone

MAAG3173

conjugation

N/A

Applications

ELISA,WB,IFA,IHC

Format

Clear, colorless solution in phosphate buffered saline, pH 7.2.

Storage

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Antigen Gene Information

Gene Name	IRAK1 interleukin-1 receptor-associated kinase 1 [ Homo sapiens ]
Official Symbol	IRAK1
Synonyms	IRAK1; interleukin-1 receptor-associated kinase 1; IRAK; pelle; IRAK-1; Pelle homolog;
GeneID	3654
mRNA Refseq	NM_001025242
Protein Refseq	NP_001020413
MIM	300283
UniProt ID	P51617
Chromosome Location	Xq28
Pathway	Activated TLR4 signalling, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; IL-1 Signaling Pathway, organism-specific biosystem;
Function	ATP binding; NF-kappaB-inducing kinase activity; interleukin-1 receptor binding; kinase activity; nucleotide binding; protein binding; protein heterodimerization activity; protein homodimerization activity; protein homodimerization activity; protein kinase activity; protein kinase activity; protein serine/threonine kinase activity; protein serine/threonine kinase activity; ubiquitin-protein ligase activity;

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Mouse Anti-Human IRAK1 Monoclonal Antibody, MAAG3173

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