Recombinant Human CFHR1, His-tagged

• Cat.No.: CFHR1-268H
• Product Overview: Recombinant Human CFHR1 (Met1-Arg330) was expressed with His tag at the C-terminus.

Specification

• Cat. No.: CFHR1-268H
• Description: CFHR1 is a member of the complement factor H protein family. It is a secreted protein which binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. The human complement factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1(FHL-1) and five factor H-related proteins (CFHR-1 to -5). CFHR1 might be involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism.
• Source: Human Cells
• Molecular Mass: The recombinant human CFHR1 consists of 323 amino acids and predicts a molecular mass of 37.2 KDa. It migrates as an approximately 45 KDa band in SDS-PAGE under reducing conditions.
• Predicted N terminal: Glu 19
• Formulation: Lyophilized from a 0.2μm filtered solution of PBS, pH 7.4.
• Purity: >95% as determined by SDS­PAGE
• Endotoxin: <1.0 EU per μg of the protein as determined by the LAL method
• Storage: Store it under sterile conditions at -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: CFHR1

Gene Information

• Gene Name: CFHR1 complement factor H-related 1 [ Homo sapiens ]
• Synonyms: CFHR1; complement factor H-related 1; CFHL1, CFHL1P, CFHR1P, complement factor H related 1 pseudogene , H factor (complement) like 1 , H factor (complement) like 2 , HFL1, HFL2; complement factor H-related protein 1; CFHL; FHR1; H36 1; H36 2
• Gene ID: 3078
• mRNA Refseq: NM_002113
• Protein Refseq: NP_002104
• MIM: 134371
• UniProt ID: Q03591
• Chromosome Location: 1q32