Mouse Anti-TREM1 Monoclonal Antibody
Cat.No. : | DMABT-H18610 |
Product Overview : | Mouse Anti-TREM1 Monoclonal Antibody |
- Specification
- Gene Information
- Related Products
Antigen Description : | TREM-1 is a 30 kD glycoprotein also known as triggering receptor expressed on myeloid cells 1, and triggering receptor expressed on monocytes 1. It is a Type I membrane protein that contains an immunoglobulin-like V-type domain. Alternatively spliced protein variant may be secreted. TREM-1 is highly expressed on peripheral blood myeloid cells (particularly mature monocytes and granulocytes); TREM-1 expression can be further upregulated by bacteria, fungi and lipopolysaccharide. TREM-1 has been shown to interact with the adaptor protein DAP12 to stimulate neutrophil and monocyte-mediated inflammatory responses through the triggering and release of pro-inflammatory cytokines and chemokines. TREM-1 is thought to amplify inflammatory responses to fungal and bacterial infections and potentiate septic shock. |
Target : | TREM1 |
Immunogen : | Recombinant human TREM-1 |
Host : | Mouse |
Isotype : | IgG1, kappa |
species : | Human |
Conjugation : | APC |
Applications : | Flow Cyt |
Preparation : | The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody. |
Usage recommendation : | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis.Test size products are transitioning from 20 μl to 5 μl per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 μl staining volume or per 100 μl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Read more at www.biolegend.com/testsize regarding the test size change. |
Storage : | The antibody solution should be stored undiluted at 4 °C and protected from prolonged exposure to light.Do not freeze. |
Size : | 100 tests |
Gene Name : | TREM1 triggering receptor expressed on myeloid cells2[ Homo sapiens ] |
Official Symbol : | TREM1 |
Synonyms : | TREM1; triggering receptor expressed on myeloid cells 1; CD354; TREM 1; triggering-receptor TREM1; triggering receptor expressed on monocytes 1; TREM-1; |
Gene ID : | 54210 |
mRNA Refseq : | NM_001242589 |
Protein Refseq : | NP_001229518 |
MIM : | 605085 |
UniProt ID : | Q9NP99 |
Chromosome Location : | 6p21.1 |
Pathway : | Cell surface interactions at the vascular wall, organism-specific biosystem; Hemostasis, organism-specific biosystem; |
Function : | receptor activity; |
Products Types
◆ Recombinant Protein | ||
TREM1-886H | Recombinant Human TREM1 protein(Met1-Arg200), His&hFc-tagged | +Inquiry |
TREM1-485H | Recombinant Human TREM1 Protein, His-tagged | +Inquiry |
TREM1-116H | Recombinant Human TREM1 Protein, C-His-tagged | +Inquiry |
TREM1-3842H | Recombinant Human TREM1 protein(Met1-Arg200), His-tagged | +Inquiry |
TREM1-1781R | Recombinant Rhesus Monkey TREM1 Protein, hIgG4-tagged | +Inquiry |
◆ Lysates | ||
TREM1-2140HCL | Recombinant Human TREM1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionTREM1 protein can enhance inflammatory response during infection, but its specific relationship with antibacterial effect still needs further study.
High expression of the TREM1 protein in lung disease can trigger an excessive inflammatory response, and controlling its activity may help reduce the symptoms and inflammatory damage of lung disease.
When bacterial infection occurs, the expression of the TREM1 protein increases, which enhances the inflammatory response, which helps clear the infection and regulate the inflammatory process.
TREM1 protein is involved in immune response processes such as macrophage activation, release of inflammatory mediators, and recruitment and regulation of immune cells.
The study of TREM1 protein helps to understand the regulatory mechanism of inflammatory response and provide new targets and strategies for the treatment of inflammatory diseases.
High expression of the TREM1 protein is associated with the development and prognosis of certain diseases and can therefore serve as a biomarker for predicting and monitoring disease progression.
Customer Reviews (3)
Write a reviewThe exceptional stability of TREM1 makes it an invaluable tool for a wide range of applications.
Manufacturer's commitment to environmental sustainability is evident in its production processes, using green and renewable resources.
TREM1 has a short half-life, making it more effective and less likely to cause side effects compared to other similar proteins.
Ask a Question for All TREM1 Products
Required fields are marked with *
My Review for All TREM1 Products
Required fields are marked with *
Inquiry Basket