Mouse Anti-LTBR Monoclonal Antibody
Cat.No. : | DMABT-H19157 |
Product Overview : | Mouse Anti-LTBR Monoclonal Antibody |
- Specification
- Gene Information
- Related Products
Antigen Description : | LT-betaR, also known as lymphotoxin beta receptor and tumor necrosis factor receptor superfamily member4is a 47 kD transmembrane protein containing4TNF receptor domains. The LT-betaR is a receptor for the heterotrimeric lymphotoxin complex (composed of LTalpha and LTbeta as well as LIGHT. LT-betaR is highly expressed in the lung, liver, and kidney and moderately expressed expressed in the heart and testes. LT-betaR is weakly expressed in the brain, thymus, spleen, and lymph nodes. The cytoplasmic tail of LT-betaR interacts with TRAF3, TRAF4, and TRAF5 as well as the hepatitis C virus core protein. Ligand binding to LT-betaR has been shown to induce apoptosis (via TRAF3 and TRAF5) and play a role in the development of lymphoid organs. |
Target : | LTBR |
Immunogen : | Human LT-beta R Fc protein |
Host : | Mouse |
Isotype : | IgG2b, kappa |
species : | Human |
Clone : | 42H5E9 |
Conjugation : | N/A |
Applications : | Flow Cyt,WB,IP |
Preparation : | The LEAF (Low Endotoxin, Azide-Free) antibody was Purified by affinity chromatography. |
Usage recommendation : | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤2.0 μg per million cells in 100 μl volume. It is recommended that the reagent be titrated for optimal performance for each application. |
Concentration : | 1.0 mg/ml |
Storage : | The antibody solution should be stored undiluted at 4 °C. This LEAF solution contains no preservative; handle under aseptic conditions. |
Size : | 500 μg |
Gene Name : | LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) [ Homo sapiens ] |
Official Symbol : | LTBR |
Synonyms : | LTBR; lymphotoxin beta receptor (TNFR superfamily, member 3); D12S370; tumor necrosis factor receptor superfamily member 3; TNF R III; TNFCR; TNFR RP; TNFR2 RP; TNFRSF3; TNF-RIII; TNFR-III; lymphotoxin B receptor; lymphotoxin-beta receptor; TNFR superfamily, member 3; tumor necrosis factor C receptor; tumor necrosis factor receptor type III; tumor necrosis factor receptor 2-related protein; tumor necrosis factor receptor superfamily, member 3; CD18; TNFR-RP; TNFR2-RP; LT-BETA-R; TNF-R-III; |
Gene ID : | 4055 |
mRNA Refseq : | NM_002342 |
Protein Refseq : | NP_002333 |
MIM : | 600979 |
UniProt ID : | P36941 |
Chromosome Location : | 12p13 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; Intestinal immune network for IgA production, organism-specific biosystem; Intestinal immune network for IgA production, conserved biosystem; |
Function : | identical protein binding; protein binding; receptor activity; |
Products Types
◆ Recombinant Protein | ||
LTBR-2411R | Recombinant Rhesus Macaque LTBR Protein, His (Fc)-Avi-tagged | +Inquiry |
LTBR-235H | Recombinant Human LTBR Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
LTBR-1288R | Recombinant Rat LTBR protein(Met1-Ala218), hFc-tagged | +Inquiry |
LTBR-369H | Recombinant Human LTBR Protein, Fc-tagged | +Inquiry |
LTBR-190H | Recombinant Human LTBR protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
LTBR-1229CCL | Recombinant Cynomolgus LTBR cell lysate | +Inquiry |
LTBR-1052RCL | Recombinant Rat LTBR cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket