Address: 45-1 Ramsey Road, Shirley, NY 11967, USA    USA: 1-631-559-9269  1-631-448-7888   Fax: 1-631-938-8127  Europe: 44-207-048-3343   Email: info@creative-biomart.com
Home > Products > Antibody > Monoclonal Antibodies > Mouse Anti-IL32 Monoclonal Antibody

Mouse Anti-IL32 Monoclonal Antibody

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Human(42)
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Biotin(1)
His(4)
N/A(1)
Cat.No.:
DMABT-H19213
Product Overview:
Mouse Anti-IL32 Monoclonal Antibody
Antigen Description:
Interleukin 32 (IL-32),previously known as a transcript (NK4), is produced by mitogen-activated lymphocytes, by IFNgamma-activated epithelial cells or by IL-12 and IL-18-activated NK cells.Its expression is increased following activation of T-cells by mitogens or the activation of NK cells by IL-2.IL-32 activates NF-kappa -B and p38 MAPK cytokine signal pathways. It has been suggested that IL-32 may play a role in autoimmune and inflammatory diseases such as rheumatoid arthritis.IL-32 is unusual in that it does not share sequence homology with known cytokine families and is highly expressed in immune tissues. IL-32 exists in at least four differentially spliced isoforms (alpha, beta, gamma and delta)with predicted molecular weight: ~26 kD.IL-32alpha is the shortest and most abundant of four potential splice variants of the pro-inflammatory cytokine IL-32.Potential modifications include myristoylation and N-glycosylation. Transfected IL-32 alpha was more likely to be cell-associated as compared to IL-32beta, suggesting an intracellular function.
Target:
IL32
Immunogen:
Recombinant human IL-32 alpha
Host:
Mouse
Isotype:
IgG1, kappa
species:
Human
Conjugation:
Biotin
Applications:
ELISA,Flow Cyt,WB,IFA,IP
Preparation:
The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Usage recommendation:
Each lot of this antibody is quality control tested by ELISA assay. For use as an ELISA detection antibody, a concentration range of 0.2-1 μg/ml is recommended. To obtain a linear standard curve, serial dilutions of human IL-32 recombinant protein ranging from 2000 to26pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application
Concentration:
0.5 mg/ml
Storage:
The antibody solution should be stored undiluted at 4 °C.Do not freeze.
Size:
50 μg


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Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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