Mouse Anti-IFNGR2 Monoclonal Antibody

• Cat.No.: DMABT-H19226
• Product Overview: Mouse Anti-IFNGR2 Monoclonal Antibody

Specification

• Antigen Description: Interferon-gamma is a potent multifunctional cytokine which is secreted primarily by activated NK cells and T cells. Originally characterized based on anti-viral activities, IFN-gamma also exerts anti-proliferative, immunoregulatory, and proinflammatory activities. IFN-gamma can upregulate MHC class I and II antigen expression by antigen-presenting cells.
• Target: IFNGR2
• Immunogen: E. coli- expressed, recombinant human IFN-gamma
• Host: Mouse
• Isotype: IgG1, kappa
• species: Human
• Clone: 5T.C4
• Conjugation: N/A
• Applications: ELISA,ELISPOT,Neut
• Preparation: The LEAF (Low Endotoxin, Azide-Free) antibody was Purified by affinity chromatography.
• Usage recommendation: Each lot of this antibody is quality control tested by ELISA assay. For ELISPOT capture applications, a concentration range of 0.5-2 μg/ml is recommended. For ELISA capture applications, a concentration range of 1-4 μg/ml is recommended. To obtain a linear standard curve, serial dilutions of IFN-gamma recombinant protein ranging from 1000 to 8 pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application.
• Concentration: 1.0 mg/ml
• Storage: The antibody solution should be stored undiluted at 4 °C. This LEAF solution contains no preservative; handle under aseptic conditions.
• Size: 50 μg;500 μg

Gene Information

• Gene Name: IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) [ Homo sapiens ]
• Official Symbol: IFNGR2
• Synonyms: IFNGR2; interferon gamma receptor 2 (interferon gamma transducer 1); IFNGT1; interferon gamma receptor 2; AF 1; IFN-gamma-R2; IFN-gamma receptor 2; interferon gamma transducer 1; interferon gamma receptor beta chain; interferon gamma receptor accessory factor 1; interferon gamma receptor accessory factor-1; AF-1; IFGR2
• Gene ID: 3460
• mRNA Refseq: NM_005534
• Protein Refseq: NP_005525
• MIM: 147569
• UniProt ID: P38484
• Chromosome Location: 21q22.1
• Pathway: Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem
• Function: interferon-gamma receptor activity; receptor activity