Mouse Anti-IL12B Monoclonal Antibody

Cat.No.: DMABT-H19254
Product Overview: Mouse Anti-IL12B Monoclonal Antibody
Target: IL12B
Immunogen: CHO-expressed, recombinant human IL-12 p70 heterod
Host: Mouse
Isotype: IgG1, kappa
species: Human
Clone: D22.6
Conjugation: Alexa Fluor 488
Applications: N/A
Preparation: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor 488 under optimal conditions. The solution is free of unconjugated Alexa Fluor 488.
Usage recommendation: Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 μl per 106cells in 100 μl volume. It is recommended that the reagent be titrated for optimal performance for each application. * Alexa Fluor 488 has a maximum emission of 519 nm when it is excited at 488 nm. ** Alexa Fluor is a registered trademark of Molecular Probes, Inc. Alexa Fluor dye antibody conjugates are sold under license from Molecular Probes, Inc. for research use only, except for use in combination with microarrays and high content screening, and are covered by pending and issued patents.View full statement regarding label licenses
Storage: The antibody solution should be stored undiluted at 4 °C and protected from prolonged exposure to light.Do not freeze.
Size: 100 tests
Gene Name: IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) [ Homo sapiens ]
Official Symbol: IL12B
Synonyms: IL12B; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); NKSF2; interleukin-12 subunit beta; CLMF; CLMF2; cytotoxic lymphocyte maturation factor 2; p40; IL 12B; IL12; subunit p40; interleukin 12; interleukin 12 beta chain; natural killer cell stimulatory factor; 40 kD subunit; natural killer cell stimulatory factor 2; NKSF; CLMF p40; IL-12 subunit p40; IL12, subunit p40; interleukin 12, p40; interleukin-12 beta chain; NK cell stimulatory factor chain 2; cytotoxic lymphocyte maturation factor 40 kDa subunit; natural killer cell stimulatory factor, 40 kD subunit; IL-12B;
Gene ID: 3593
mRNA Refseq: NM_002187
Protein Refseq: NP_002178
MIM: 161561
UniProt ID: P29460
Chromosome Location: 5q31.1-q33.1
Pathway: African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem;
Function: contributes_to cytokine activity; cytokine receptor activity; contributes_to growth factor activity; identical protein binding; interleukin-12 alpha subunit binding; interleukin-12 receptor binding; contributes_to interleukin-12 receptor binding; contributes_to interleukin-23 receptor binding; protein binding; protein heterodimerization activity; protein homodimerization activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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