Recombinant Human RAMP3, His-tagged

• Cat.No.: RAMP3-7526H
• Product Overview: Recombinant human RAMP3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Antigen Description: RAMP3, also known as receptor activity modifying protein 3, is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). It is required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR can function as either a calcitonin gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl
• Molecular Mass: 13.0 kDa(116aa) confirmed by MALDI-TOF
• Protein length: 24-118aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MRAGGCNETG MLERLPLCGK AFADMMGKVD VWKWCNLSEF IVYYESFTNC TEMEANVVGC YWPNPLAQGF ITGIHRQFFS NCTVDRVHLE DPPDEV
• Purity: >90% as determined by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: RAMP3 receptor (G protein-coupled) activity modifying protein 3 [ Homo sapiens ]
• Official Symbol: RAMP3
• Synonyms: RAMP3; receptor (G protein-coupled) activity modifying protein 3; receptor (calcitonin) activity modifying protein 3 , receptor activity modifying protein 3; receptor activity-modifying protein 3; CRLR activity-modifying protein 3; receptor activity modifying protein 3; receptor-activity-modifying protein 3; receptor (calcitonin) activity modifying protein 3; calcitonin receptor-like receptor activity modifying protein 3; calcitonin-receptor-like receptor activity-modifying protein 3
• Gene ID: 10268
• mRNA Refseq: NM_005856
• Protein Refseq: NP_005847
• MIM: 605155
• UniProt ID: O60896
• Chromosome Location: 7p13-p12
• Pathway: Calcitonin-like ligand receptors, organism-specific biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Myometrial Relaxation and Contraction Pathways, organism-specific biosystem; Signal Transduction, organism-specific biosystem
• Function: coreceptor activity; protein binding; protein transporter activity; receptor activity