Recombinant Human WLS, His-tagged
Cat.No. : | WLS-7571H |
Product Overview : | Recombinant human WLS protein, fused to His-tag at N-terminus, was expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Antigen Description : | WLS, a Wnt trafficking regulator, is a multipass transmembrane protein that regulates the sorting and secretion of Wnt protein. It is required for organogenesis during embryogenesis and for the establishment of the anterior-posterior axis. WLS promotes various cancers such as glioma tumourigenesis. The gene encoding WLS maps to human chromosome 1 and is expressed as multiple alternatively spliced isoforms. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol |
Molecular Mass : | 17.8 kDa (155aa) |
Protein length : | 101-232aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMEMSPWF QFMLFILQLD IAFKLNNQIR ENAEVSMDVS LAYRDDAFAE WTEMAHERVP RKLKCTFTSP KTPEHEGRYY ECDVLPFMEI GSVAHKFYLL NIRLPVNEKK KINVGIGEIK DIRLVGIHQN GGFTK |
Purity : | >90% as determined by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml |
Gene Name : | WLS wntless homolog (Drosophila) [ Homo sapiens ] |
Official Symbol : | WLS |
Synonyms : | WLS; EVI; MRP; GPR177; C1orf139; protein wntless homolog; G protein-coupled receptor 177; integral membrane protein GPR177; protein evenness interrupted homolog; putative NFkB activating protein 373; putative NF-kappa-B-activating protein 373; wntless homolog (Drosophila) |
Gene ID : | 79971 |
mRNA Refseq : | NM_001002292 |
Protein Refseq : | NP_001002292 |
MIM : | 611514 |
UniProt ID : | Q5T9L3 |
Chromosome Location : | 1p31.3 |
Function : | Wnt-protein binding; protein binding; signal transducer activity |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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