Recombinant Human POP4, His-tagged

• Cat.No.: POP4-7581H
• Product Overview: Recombinant human POP4 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Specification

• Antigen Description: POP4 is one of the protein subunits of the small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. POP4 is localized to the nucleus and associates directly with the RNA component of these complexes. This protein is involved in processing of precursor RNAs.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol
• Molecular Mass: 27.8 kDa (243aa)
• Protein length: 1-220aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMKSVIYH ALSQKEANDS DVQPSGAQRA EAFVRAFLKR STPRMSPQAR EDQLQRKAVV LEYFTRHKRK EKKKKAKGLS ARQRRELRLF DIKPEQQRYS LFLPLHELWK QYIRDLCSGL KPDTQPQMIQ AKLLKADLHG AIISVTKSKC PSYVGITGIL LQETKHIFKI ITKEDRLKVI PKLNCVFTVE TDGFISYIYG SKFQLRSSER SAKKFKAKGT IDL
• Purity: >85% as determined by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml

Gene Information

• Gene Name: POP4?processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) [?Homo sapiens?]
• Official Symbol: POP4
• Synonyms: POP4; RPP29; ribonuclease P protein subunit p29; hPOP4; EC 3.1.26.5; processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
• Gene ID: 10775
• mRNA Refseq: NM_006627
• Protein Refseq: NP_006618
• MIM: 606114
• UniProt ID: O95707
• Chromosome Location: 19q12
• Pathway: RNA transport; Ribosome biogenesis in eukaryotes
• Function: RNA binding; protein binding; ribonuclease P activity