Recombinant Human TARDBP, His-tagged
Cat.No. : | TARDBP-7588H |
Product Overview : | Recombinant human TARDBP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Antigen Description : | TARDBP was originally identified as a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. It has also been identified in individuals diagnosed with chronic traumatic encephalopathy, a condition that often mimics ALS and that has been associated with athletes who have experienced multiple concussions and other types of head injury. It has been shown to bind both DNA and RNA and have multiple functions in transcriptional repression, pre-mRNA splicing and translational regulation. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl |
Molecular Mass : | 33.6 kDa(296aa) confirmed by MALDI-TOF |
Protein length : | 1-260aa |
AA Sequence : | MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMSEY IRVTEDENDE PIEIPSEDDG TVLLSTVTAQ FPGACGLRYR NPVSQCMRGV RLVEGILHAP DAGWGNLVYV VNYPKDNKRK MDETDASSAV KVKRAVQKTS DLIVLGLPWK TTEQDLKEYF STFGEVLMVQ VKKDLKTGHS KGFGFVRFTE YETQVKVMSQ RHMIDGRWCD CKLPNSKQSQ DEPLRSRKVF VGRCTEDMTE DELREFFSQY GDVMDVFIPK PFRAFAFVTF ADDQIAQSLC GEDLIIKGIS VHISNA |
Purity : | >90% as determined by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml |
Gene Name : | TARDBP TAR DNA binding protein [ Homo sapiens ] |
Official Symbol : | TARDBP |
Synonyms : | TARDBP; TAR DNA binding protein; TAR DNA-binding protein 43; ALS10; TDP 43; TAR DNA-binding protein-43; TDP-43; |
Gene ID : | 23435 |
mRNA Refseq : | NM_007375 |
Protein Refseq : | NP_031401 |
MIM : | 605078 |
UniProt ID : | Q13148 |
Chromosome Location : | 1p36.22 |
Function : | DNA binding; RNA binding; double-stranded DNA binding; mRNA 3-UTR binding; nucleotide binding; protein binding; sequence-specific DNA binding transcription factor activity; |
Products Types
◆ Recombinant Protein | ||
TARDBP-2192H | Recombinant Human TARDBP Protein (1-396 aa), His-tagged | +Inquiry |
TARDBP-41H | Recombinant Human TARDBP Protein (Full length), N-GST-tagged | +Inquiry |
TARDBP-22H | Recombinant Human TARDBP Protein | +Inquiry |
Tardbp-6294M | Recombinant Mouse Tardbp Protein, Myc/DDK-tagged | +Inquiry |
TARDBP-116H | Recombinant Human TARDBP Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
TARDBP-1251HCL | Recombinant Human TARDBP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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