Rat Anti-Havcr1 Monoclonal Antibody
Cat.No. : | DMAB36384 |
Product Overview : | Rat Anti-Havcr1 Monoclonal Antibody |
- Specification
- Gene Information
- Related Products
Antigen Description : | Tim-1 is highly expressed by activated CD4+ T cells, and acts as a positive/negative co-stimulatory molecule of T cell proliferation, cytokine production and tolerance abrogation, and is the receptor for Tim-4, expressed on APCs. Tim-1 expression is greater on Th2 than Th1 cells, and studies have shown that interaction between Tim-1 on Th2 cells and Tim-4 on dendritic cells (DCs), enhances Th2 cell function, and have implicated Tim-1 as a critical player in the development of atopic disease, and in particular airway hypersensitivity. |
specificity : | It specifically recognises mouse Tim-1 (T-cell immunoglobulin mucin 1), a cell surface glycoprotein and member of the immunoglobulin superfamily, which was first identified as the hepatitis A virus cellular receptor (HAVCR), and is highly expressed in the liver (isoform Tim-1a) and the kidneys (isoform Tim-1b). |
Target : | Havcr1 |
Immunogen : | Full-length mouse Tim-1-Ig, containing both the IgV and mucin domains of Tim-1. |
Host : | Rat |
Isotype : | IgG2a |
species : | Mouse |
Clone : | SNU2-20 |
Purification : | Purified IgG |
Conjugation : | N/A |
Applications : | ELISA,Flow Cyt,IFA |
Dilution : | Flow Cytometry:1/25 - 1/200 |
Preparation : | Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant |
Protein Concentration : | 1 mg/ml |
Storage : | Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
Preservative : | 0.09% Sodium Azide (NaN3) |
Shelf life : | 18 months from date of despatch. |
Size : | 0.1 mg |
Gene Name : | Havcr1 hepatitis A virus cellular receptor 1 [ Mus musculus ] |
Official Symbol : | Havcr1 |
Synonyms : | HAVCR1; hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; TIMD-1; HAVcr-1; kidney injury molecule 1; t cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; t cell immunoglobulin and mucin domain-containing protein 1; Tim1; KIM-1; TIM-1; Timd1; AI503787; |
Gene ID : | 171283 |
mRNA Refseq : | NM_001166631 |
Protein Refseq : | NP_001160103 |
Function : | receptor activity; |
Products Types
◆ Native Protein | ||
HB-01H | Native Human HB Protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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