Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Rat Anti-Havcr1 Monoclonal Antibody

Cat.No. : DMAB36384
Product Overview : Rat Anti-Havcr1 Monoclonal Antibody
  • Specification
  • Gene Information
  • Related Products
Antigen Description : Tim-1 is highly expressed by activated CD4+ T cells, and acts as a positive/negative co-stimulatory molecule of T cell proliferation, cytokine production and tolerance abrogation, and is the receptor for Tim-4, expressed on APCs. Tim-1 expression is greater on Th2 than Th1 cells, and studies have shown that interaction between Tim-1 on Th2 cells and Tim-4 on dendritic cells (DCs), enhances Th2 cell function, and have implicated Tim-1 as a critical player in the development of atopic disease, and in particular airway hypersensitivity.
specificity : It specifically recognises mouse Tim-1 (T-cell immunoglobulin mucin 1), a cell surface glycoprotein and member of the immunoglobulin superfamily, which was first identified as the hepatitis A virus cellular receptor (HAVCR), and is highly expressed in the liver (isoform Tim-1a) and the kidneys (isoform Tim-1b).
Target : Havcr1
Immunogen : Full-length mouse Tim-1-Ig, containing both the IgV and mucin domains of Tim-1.
Host : Rat
Isotype : IgG2a
species : Mouse
Clone : SNU2-20
Purification : Purified IgG
Conjugation : N/A
Applications : ELISA,Flow Cyt,IFA
Dilution : Flow Cytometry:1/25 - 1/200
Preparation : Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Protein Concentration : 1 mg/ml
Storage : Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Preservative : 0.09% Sodium Azide (NaN3)
Shelf life : 18 months from date of despatch.
Size : 0.1 mg
Gene Name : Havcr1 hepatitis A virus cellular receptor 1 [ Mus musculus ]
Official Symbol : Havcr1
Synonyms : HAVCR1; hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; TIMD-1; HAVcr-1; kidney injury molecule 1; t cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; t cell immunoglobulin and mucin domain-containing protein 1; Tim1; KIM-1; TIM-1; Timd1; AI503787;
Gene ID : 171283
mRNA Refseq : NM_001166631
Protein Refseq : NP_001160103
Function : receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All H Products

Required fields are marked with *

My Review for All H Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends