Catalog # or name ...
Mouse Anti-IDH3A Monoclonal Antibody
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.
Full length human recombinant protein of human IDH3A (NP_005521) produced in HEK293T cell.
Purified from mouse ascites fluids by affinity chromatography
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Shipped at 4°C. Upon delivery store at -20°C. Dilute in PBS (pH7.3) before use. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
Antigen Gene Information
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha [ Homo sapiens ]
IDH3A; isocitrate dehydrogenase 3 (NAD+) alpha; isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; H IDH alpha; isocitrate dehydrogenase (NAD+) alpha chain; isocitrate dehydrogenase [NAD] subunit alpha; mitochondrial; isocitric dehydrogenase; NAD(H) specific isocitrate dehydrogenase alpha subunit; NAD+ specific ICDH; H-IDH alpha; NAD+-specific ICDH; NAD(+)-specific ICDH subunit alpha; isocitric dehydrogenase subunit alpha; NAD(H)-specific isocitrate dehydrogenase alpha subunit;
Citrate cycle (TCA cycle), organism-specific biosystem; Citrate cycle (TCA cycle), conserved biosystem; Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate, organism-specific biosystem; Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate, conserved biosystem; Citric acid cycle (TCA cycle), organism-specific biosystem;
NAD binding; isocitrate dehydrogenase (NAD+) activity; magnesium ion binding; oxidoreductase activity; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;
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