Mouse Anti-Human IDH3A Monoclonal Antibody

Cat.No.

CAB-8745MH

Product Overview

Mouse Anti-IDH3A Monoclonal Antibody

Antigen Description

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

Target

IDH3A

Immunogen

Full length human recombinant protein of human IDH3A (NP_005521) produced in HEK293T cell.

Host

Mouse

Isotype

IgG1

Species

Human

Clone

cdO441M

Purification

Purified from mouse ascites fluids by affinity chromatography

conjugation

N/A

Applications

WB

Buffer

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage

Shipped at 4°C. Upon delivery store at -20°C. Dilute in PBS (pH7.3) before use. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.

Antigen Gene Information