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Active Recombinant Human ACVR2A, His tagged

Cat.No. : ACVR2A-3819H
Product Overview : Recombinant Human ACVR2A (NP_001607.1) extracellular domain (Met 1-Pro 134), fused with a polyhistidine tag at the C-terminus, was produced in Human Cell.
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Source : HEK293
Species : Human
Tag : His
Form : Lyophilized from sterile 50 mM Tris, pH 8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Bio-activity : Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation.
The ED50 for this effect is typically 0.4-3 µg/mL in the presence of 10 ng/mL recombinant Activin A.
Molecular Mass : The recombinant human ACVR2A comprises 126 amino acids and predicts a molecular mass of 14.9 kDa. As a result of glycosylation, the apparent molecular mass of the protein is approximately 35-40 kDa in SDS-PAGE under reducing conditions.
Protein Length : Met 1-Pro 134
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : ≥ 97 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : ACVR2A activin A receptor, type IIA [ Homo sapiens ]
Official Symbol : ACVR2A
Synonyms : ACVR2A; activin A receptor, type IIA; activin A receptor, type II , ACVR2; activin receptor type-2A; ACTRII; ACVR2;
Gene ID : 92
mRNA Refseq : NM_001616
Protein Refseq : NP_001607
MIM : 102581
UniProt ID : P27037

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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