Recombinant Human ADP-Ribosylation Factor-Like 1, His-tagged

• Cat.No.: ARL1-4200H
• Product Overview: ARL1 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 201 amino acids (1-181 a.a.) and having a molecular mass of 22.5 kDa. The ARL1 is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

Specification

• Cat. No.: ARL1-4200H
• Description: ARL1 is part of the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally associated to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, control intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. ARL1 is a weak stimulator of PLD and CT in a phospholipid dependent manner. ARL1 is a GTP-binding protein that has low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. ARL1 is involved in the Golgi apparatus.
• Source: Human
• Host: Escherichia Coli.
• Form: 0.25mg/ml solution containing 20mM Tris pH-8, 1mM DTT & 10% glycerol.
• Purity: Greater than 95.0% as determined by SDS-PAGE.
• Physical Appearance: Sterile filtered colorless solution.
• Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MGGFFSSIFS SLFGTREMRI LILGLDGAGK TTILYRLQVG EVVTTIPTIG FNVETVTYKN LKFQVWDLGG QTSIRPYWRC YYSNTDAVIY VVDSCDRDRI GISKSELVAM LEEEELRKAI LVVFANKQDM EQAMTSSEMA NSLGLPALKD RKWQIFKTSA TKGTGLDEAM EWLVETLKSR Q.
• Storage: ARL1 Human although stable at 4C for 1 week, should be stored desiccated below -18C. Please prevent freeze thaw cycles.

Gene Information

• Gene Name: ARL1 ADP-ribosylation factor-like 1 [ Homo sapiens ]
• Official Symbol: ARL1
• Synonyms: ARL1; ADP-ribosylation factor-like 1; ARFL1; ADP-ribosylation factor-like protein 1
• Gene ID: 400
• mRNA Refseq: NM_001177
• Protein Refseq: NP_001168
• MIM: 603425
• UniProt ID: P40616
• Chromosome Location: 12q23.2
• Function: GTP binding; GTPase activity; enzyme activator activity; metal ion binding; nucleotide binding; protein binding