Catalog # or name ...
A DNA sequence
encoding the human BLK ( NP_001706.2 ) ( Met 1 - Pro 505 ) was fused with the
GST tag at the N-terminus.
BLK is a member of
the protein kinase superfamily, Tyr protein kinase family and SRC subfamily.
BLK is expressed in lymphatic organs, pancreatic islets, Leydig cells,
striate ducts of salivary glands and hair follicles.
sterile 20mM Tris, 500mM NaCl, 5mM GSH, pH 7.4. Normally 5 % - 8 % trehalose
and mannitol are added as protectants before lyophilization. Specific
concentrations are included in the hardcopy of COA.
> 88 % as
determined by SDS-PAGE
activity of BLK was determined to be 10 nmol/min/mg using a Poly ( Glu: Tyr,
4:1 ) synthetic peptide substrate.
EU per μg protein as determined by the LAL method
are stable for up to twelve months from date of receipt at -70oC.
Predicted N terminal
recombinant human BLK/GST chimera consists of 730 amino acids and migrates as
an approximatly 84 kDa band as predicted in SDS-PAGE under reducing
Store it under
sterile conditions at -70oC
upon receiving. Recommend to aliquot the protein into smaller quantities for
optimal storage. Avoid repeated freeze-thaw cycles.
Antigen Gene Information
BLK B lymphoid
tyrosine kinase [ Homo sapiens ]
BLK; B lymphoid tyrosine kinase; MODY11; MGC10442;
tyrosine-protein kinase Blk; p55-Blk; OTTHUMP00000115909; OTTHUMP00000229490;
b lymphocyte kinase; BLK nonreceptor tyrosine kinase; EC 18.104.22.168; Tyrosine-protein kinase
Alpha-synuclein signaling; B Cell Receptor
Signaling Pathway; CXCR4-mediated signaling events; Class I PI3K signaling
events; EPHA forward signaling; Ephrin B reverse signaling; Focal Adhesion;
Glypican 1 network; IL-7 Signaling Pathway; PDGFR-beta signaling pathway;
Regulation of p38-alpha and p38-beta; Signaling events mediated by PTP1B;
Thromboxane A2 receptor signaling; amb2 Integrin signaling
ATP binding; non-membrane spanning protein
tyrosine kinase activity; nucleotide binding; protein tyrosine kinase
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