Recombinant Human CDKN1B, His-tagged
Cat.No. : | CDKN1B-4729H |
Product Overview : | Recombinant human CDKN1B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
- Specification
- Gene Information
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Cat. No. : | CDKN1B-4729H |
Description : | CDKN1B, also known as cyclin-dependent kinase inhibitor 1B, belongs to the Cip/Kip family of cyclin dependent kinase (Cdk) inhibitor proteins. This protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. It is often referred to as a cell cycle inhibitor protein because its major function is to stop or slow down the cell division cycle. |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol |
Molecular Weight : | 24.2 kDa (218aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher) |
Purity : | > 90% by SDS - PAGE |
Concentration : | 0.25 mg/ml (determined by Bradford assay) |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MSNVRVSNGS PSLERMDARQ AEHPKPSACR NLFGPVDHEE LTRDLEKHCR DMEEASQRKW NFDFQNHKPL EGKYEWQEVE KGSLPEFYYR PPRPPKGACK VPAQESQDVS GSRPAAPLIG APANSEDTHL VDPKTDPSDS QTGLAEQCAG IRKRPATDDS STQNKRANRT EENVSDGSPN AGSVEQTPKK PGLRRRQT |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Pathways : | Cell cycle; Chronic myeloid leukemia; ErbB signaling pathway; Pathways in cancer; Prostate cancer; Small cell lung cancer |
Gene Name : | CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) [ Homo sapiens ] |
Official Symbol : | CDKN1B |
Synonyms : | CDKN1B; cyclin-dependent kinase inhibitor 1B (p27, Kip1); KIP1; MEN4; CDKN4; MEN1B; P27KIP1; cyclin -dependent kinase inhibitor 1B; p27Kip1; Cyclin-dependent kinase inhibitor p27 |
Gene ID : | 1027 |
mRNA Refseq : | NM_004064 |
Protein Refseq : | NP_004055 |
MIM : | 600778 |
UniProt ID : | P46527 |
Chromosome Location : | 12p13.1-p12 |
Function : | cyclin-dependent protein kinase inhibitor activity; protein binding; protein kinase inhibitor activity; transforming growth factor beta receptor, cytoplasmic mediator activity |
Products Types
◆ Recombinant Protein | ||
CDKN1B-568H | Recombinant Human CDKN1B Protein, His (Fc)-Avi-tagged | +Inquiry |
CDKN1B-620R | Recombinant Rhesus Macaque CDKN1B Protein, His (Fc)-Avi-tagged | +Inquiry |
CDKN1B-1056H | Recombinant Human CDKN1B Protein, GST-Tagged | +Inquiry |
Cdkn1b-870M | Recombinant Mouse Cdkn1b Protein, MYC/DDK-tagged | +Inquiry |
CDKN1B-1535M | Recombinant Mouse CDKN1B Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CDKN1B-7617HCL | Recombinant Human CDKN1B 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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