Recombinant Human Etythropoietin Receptor, Fc-tagged
Cat.No. : | EPOR-4114H |
Product Overview : | A DNA sequence encoding the extracellular domain ( Met 1 - Pro 250 ) of human EPOR ( NP_000112.1 ) linked with the extracellular domain ( Trp 17 - Trp 443 ) of human CD131 ( NP_000386.1 ) by a peptide linker was fused with the Fc region of human IgG1 at the C-terminus. |
- Specification
- Gene Information
- Related Products
Cat. No. : | EPOR-4114H |
Description : | EPOR is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 1 subfamily. |
Source : | Human |
Host : | Human Cells |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
Purity : | > 90 % as determined by SDS-PAGE |
Endotoxin : | < 1.0 EU per μg protein as determined by the LAL method |
Stability : | Samples are stable for up to twelve months from date of receipt at -70°C. |
Predicted N terminal : | Ala 25 |
Molecular Mass : | The recombinant human EPOR&CD131 / Fc chimera is a disulfide-linked homodimer of EPOR & CD131-Fc heterodimer. The reduced EPOR & CD131-Fc comprises 906 amino acids and has a calculated molecular mass of 101 kDa. As a result of glycosylation, the apparent molecular mass of the recombinant protein is approximately 125 kDa in SDS-PAGE under reducing conditions. |
Storage : | Store it under sterile conditions at -70°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles. |
Pathways : | Cytokine-cytokine receptor interaction; EPO Receptor Signaling; EPO signaling pathway; Hematopoietic cell lineage; Jak-STAT siqnaling pathway; Kit Receptor Siqnaling Pathway; Paxillin-independent events mediated by a4b1 and a4b7; Siqnaling events mediated by Stem cell factor (c-Kit) |
Gene Name : | EPOR erythropoietin receptor [ Homo sapiens ] |
Official Symbol : | EPOR |
Synonyms : | EPOR; erythropoietin receptor; EPO-R; MGC138358; Erythropoietin receptor |
Gene ID : | 2057 |
mRNA Refseq : | NM_000121 |
Protein Refseq : | NP_000112 |
MIM : | 133171 |
UniProt ID : | P19235 |
Chromosome Location : | 19p13.3-p13.2 |
Function : | erythropoietin receptor activity; identical protein binding; protein binding |
Products Types
◆ Recombinant Protein | ||
EPOR-241H | Recombinant Human EPOR Protein, Fc-tagged | +Inquiry |
EPOR-1434H | Recombinant Human EPOR Protein, His-tagged | +Inquiry |
EPOR-2045H | Recombinant Human EPOR Protein, Fc/His-tagged | +Inquiry |
EPOR-3424H | Recombinant Human EPOR Protein, GST-tagged | +Inquiry |
Epor-42M | Recombinant Mouse Epor Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
EPOR-2055HCL | Recombinant Human EPOR cell lysate | +Inquiry |
EPOR-2582MCL | Recombinant Mouse EPOR cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket