Recombinant Cynomolgus Fc Fragment Of LgG, Low Affinity LIa, Receptor (CD32), AVI-tagged
Cat.No. : | FCGR2A-4108C |
Product Overview : | A DNA sequence encoding the Cynomolgus ( Macaca fascicularis ) CD32a ( AAL92096.1 ) extracellular domain ( Met 1 - Gly 220 ) was fused with a c-terminal polyhistidine tagged AVI tag at the C-terminus. |
- Specification
- Gene Information
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Cat. No. : | FCGR2A-4108C |
Description : | FCGR2A is a single-pass type I membrane protein which contains two Ig-like C2-type domains. FCGR2A binds to the Fc region of immunoglobulins gamma. It is a low affinity receptor. By binding to IgG, FCGR2A initiates cellular responses against pathogens and soluble antigens. |
Source : | Cynomolgus |
Host : | Human Cells |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
Purity : | > 95 % as determined by SDS-PAGE |
Endotoxin : | < 1.0 EU per μg protein as determined by the LAL method |
Stability : | Samples are stable for up to twelve months from date of receipt at -70°C. |
Predicted N terminal : | Ala 30 |
Molecular Mass : | The recombinant cynomolgus CD32a consists of 206 amino acids and has a calculated molecular mass of 22.9 kDa. The apparent molecular mass of the recombinant protein is approximately 33-35 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
Storage : | Store it under sterile conditions at -70°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles. |
Pathways : | Fc gamma R-mediated phagocytosis; Leishmaniasis; Osteoclast differentiation; Phagosome; Staphylococcus aureus infection; Systemic lupus erythematosus; Tuberculosis |
Gene Name : | FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) [ Macaca mulatta ] |
Official Symbol : | FCGR2A |
Synonyms : | FCGR2A; Fc fragment of IgG, low affinity IIa, receptor (CD32); CD32a |
Gene ID : | 719996 |
mRNA Refseq : | XM_001118066 |
Protein Refseq : | XP_001118066 |
Chromosome Location : | 1 |
Products Types
◆ Recombinant Protein | ||
FCGR2A-301H | Recombinant Human FCGR2A Protein, His-tagged | +Inquiry |
FCGR2A-932R | Recombinant Rat FCGR2A Protein (Met1-Leu216), His-tagged | +Inquiry |
FCGR2A-543H | Recombinant Human FCGR2A Protein (H167) | +Inquiry |
FCGR2A-264C | Recombinant Cynomolgus Monkey FCGR2A Protein, His (Fc)-Avi-tagged | +Inquiry |
FCGR2A-542H | Recombinant Human FCGR2A Protein (R167) | +Inquiry |
◆ Lysates | ||
FCGR2A-678HCL | Recombinant Human FCGR2A cell lysate | +Inquiry |
FCGR2A-1996HCL | Recombinant Human FCGR2A cell lysate | +Inquiry |
FCGR2A-1926CCL | Recombinant Cynomolgus FCGR2A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionFCGR2A may influence the risk and severity of allergic reactions by modulating the immune response to allergens and antibodies involved in allergic processes.
FCGR2A participates in host defense against infectious diseases by facilitating the recognition and clearance of pathogens through antibody-mediated immune responses.
FCGR2A contributes to the understanding of immunogenetics by highlighting the genetic factors that influence immune responses and the development of immune-related diseases.
Genetic variations in FCGR2A can influence an individual's response to immunotherapy by affecting the affinity of FCGR2A for antibodies, thereby modulating immune cell activation.
FCGR2A can be targeted for therapeutic interventions through the development of drugs that modulate its activity, offering potential strategies for treating immune-related disorders.
Customer Reviews (3)
Write a reviewWith its purity and reliability, this protein is poised to contribute significantly to the success of my research objectives by providing accurate and reproducible results.
Its versatility allows for exploration of its extensive involvement in various biochemical and biological processes, providing valuable insights into its role and implications.
The FCGR2A Protein demonstrates remarkable stability and functional efficiency, making it an indispensable tool for diverse scientific applications.
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