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Recombinant Human Granulysin, His-tagged

Cat.No. : GNLY-4380H
Product Overview : GNLY Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing double His Tag and having a total molecular mass of 18.1 kDa. The GNLY is purified by proprietary chromatographic techniques.
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  • Gene Information
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Cat. No. : GNLY-4380H
Description : GNLY is part of the SAPLIP family and is located in the cytotoxic granules of T cells, which are discharged upon antigen stimulation. GNLY is localized in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. GNLY is an antimicrobial protein that kills intracellular pathogens. GNLY is active against a wide range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.
Source : Human
Host : Escherichia Coli.
Form : The GNLY protein was lyophilized from a concentrated (1mg/ml) solution containing no additives.
Purity : Greater than 95.0% as determined by SDS-PAGE.
Physical Appearance : Sterile Filtered White lyophilized (freeze-dried) powder.
Solubility : It is recommended to reconstitute the lyophilized GNLY in sterile 18Mμ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Amino acid sequence : The sequence of the first 25 N-terminal amino acids was determined and was found to be MGSSHHHHHHSSGLVPRGSHMMEGL.
Storage : Lyophilized GNLY although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution GNLY should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Gene Name : GNLY granulysin [ Homo sapiens ]
Official Symbol : GNLY
Synonyms : GNLY; granulysin; 519; LAG2; NKG5; LAG-2; D2S69E; TLA519; lymphokine LAG-2; OTTHUMP00000160682; OTTHUMP00000203266; OTTHUMP00000229037; OTTHUMP00000229039; lymphocyte-activation gene 2; T-cell activation protein 519; T-lymphocyte activation gene 519; Protein NKG5
Gene ID : 10578
mRNA Refseq : NM_006433
Protein Refseq : NP_006424
MIM : 88855
UniProt ID : P22749
Chromosome Location : 2p11.2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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