Recombinant Human Neural Cell Adhesion Molecule 1

• Cat.No.: NCAM1-4266H
• Product Overview: CD56 Human Recombinant (aa 20-220) expressed in E.coli, shows a 48 kDa band on SDS-PAGE. The CD56 is purified by proprietary chromatographic techniques.

Specification

• Cat. No.: NCAM1-4266H
• Description: Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule which is glycosylated or sialylated to produce the mature species. NCAM has been implicated as having a role in cell-cell adhesion, neurite outgrowth, synaptic plasticity, and learning and memory. NCAM (CD56) is reported to express on most neuroectodermal derived cell lines, tissues, and neoplasms such as retinoblastoma, medullblastoma, astrocytoma, and neuroblastoma. It is also expressed on some mesodermally derived tumors such as rhabdomyosarcoma and also on natural killer cells.
• Source: Human
• Host: Escherichia Coli.
• Form: CD56 at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
• Physical Appearance: Sterile Filtered clear solution.
• Storage: Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please prevent freeze-thaw cycles.

Gene Information

• Gene Name: NCAM1 neural cell adhesion molecule 1 [ Homo sapiens ]
• Official Symbol: NCAM1
• Synonyms: NCAM-1; N-CAM-1; OTTHUMP00000235666; neural cell adhesion molecule, NCAM; antigen recognized by monoclonal antibody 5.1H11; E C 2.7.11.1; CD56 antigen; neural cell adhesion molecule 1; CD56; NCAM; MSK39; NCAM1
• Gene ID: 4684
• mRNA Refseq: NM_000615
• Protein Refseq: NP_000606
• MIM: 116930
• UniProt ID: P13591
• Chromosome Location: 11q23.1
• Pathway: Axon guidance; Cell adhesion molecules (CAMs); FGF signaling pathway; Interferon Signaling; L1CAM interactions; NCAM1 interactions; Prion diseases; Signal transduction by L1