Recombinant Human NLGN3 protein, His-tagged

• Cat.No.: NLGN3-3881H
• Product Overview: Recombinant Human NLGN3 (Gln38-Ser689) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293).

Specification

• Description: Neuroligin 3 (NLGN3),a single-pass type I membrane protein ,is also known as gliotactin homolog and KIAA1480, which belongs to the type-B carboxylesterase/lipase family. As the cell surface protein,NLGN3 is involved in cell-cell-interactions via its interactions with neurexin family members. NLGN3 also plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. NLGN3 probably can promote the initial formation of synapses, but is not essential for this. Furthermore,NLGN3 may also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system.
• Source: HEK293
• Species: Human
• Tag: His
• Predicted N Terminal: Gln38
• Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose.
• Molecular Mass: The protein has a calculated MW of 74.4 kDa. The protein migrates as 100-116 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Protein length: Gln38-Ser689
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
  Please avoid repeated freeze-thaw cycles.
  This product is stable after storage at:
  -20 to -70 centigrade for 12 months in lyophilized state;
  -70 centigrade for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: NLGN3
• Official Symbol: NLGN3
• Synonyms: NLGN3; neuroligin 3; neuroligin-3; ASPGX1; AUTSX1; HNL3; KIAA1480; gliotactin homolog
• Gene ID: 54413
• mRNA Refseq: NM_001166660
• Protein Refseq: NP_001160132
• MIM: 300336
• UniProt ID: Q9NZ94