Recombinant Human Oxytocin, Prepropeptide

• Cat.No.: OXT-313H
• Product Overview: Oxytocin Human Synthetic is a single, non-glycosylated, polypeptide chain containing 9 amino acids and having a molecular mass of 1007.2 Dalton. Oxytocin has a molecular formula of C43H66N12O12S2. The OT is purified by proprietary chromatographic techniques.

Specification

• Cat. No.: OXT-313H
• Description: Human Oxytocin stimulates uterine smooth muscle contractions indirectly and stimulates the mammary glands to increase lactation without increasing the production of milk.
• Source: Human
• Form: The Oxytocin was lyophilized from a concentrated (1 mg/ml) solution with no additives.
• Purity: Greater than 98.0% as determined by RP-HPLC.
• Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
• Solubility: It is recommended to reconstitute the lyophilized Oxytocin in sterile 18Mμ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
• Amino acid sequence: Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2.
• Storage: Lyophilized Oxytocin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Neurophysin 1 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
• Pathways: Class A/1 (Rhodopsin-like receptors); G alpha (q) signalling events; GPCR downstream signaling; GPCR ligand binding; Myometrial Relaxation and Contraction Pathways; Peptide ligand-binding receptors; Signaling by GPCR; Vasopressin-like receptors

Gene Information

• Gene Name: OXT oxytocin, prepropeptide [ Homo sapiens ]
• Official Symbol: OXT
• Synonyms: OXT; OT; OT-NPI; MGC126890; MGC126892; oxytocin-neurophysin 1; neurophysin I; OTTHUMP00000030079; oxytocin, prepro- (neurophysin I); oxytocin-neurophysin I, preproprotein; oxytocin; prepropeptide
• Gene ID: 5020
• mRNA Refseq: NM_000915
• Protein Refseq: NP_000906
• MIM: 167050
• UniProt ID: P01178
• Chromosome Location: 20p13
• Function: neurohypophyseal hormone activity; oxytocin receptor binding; protein binding