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Recombinant Programmed Cell Death 1 Ligand 2, GST-tagged

Cat.No. : PDCD1LG2-4491H
Product Overview : PDCD1LG2 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain fused to a GST tag containing 274 amino acids (1-274) and having a total molecular mass of 56kDa. PDCD1LG2 is purified by proprietary chromatographic techniques.
  • Specification
  • Gene Information
  • Related Products
Cat. No. : PDCD1LG2-4491H
Description : PDCD1LG2 (B7-DC, CD273), is part of the B7 family of proteins. PDCD1LG2 plays an important regulatory role during the immune response of the host to the pathogen. PDCD1LG2 is a marker of angioimmunoblastic T-cell lymphoma and B-cell small lymphocytic lymphoma/chronic lymphocytic leukemia. HRV-16 infection or exposure to dsRNA induces epithelial PDCD1LG2. PDCD1LG2 functions as an inhibitor to T cell activation. PDCD1LG2 negatively regulates human T cell activation and therefore acts an a candidate protein for immunotherapeutic approaches aimed to attenuate pathological immune responses.
Source : Human
Host : Escherichia Coli.
Form : PDCD1LG2 is supplied in 50mM Tris-Acetate, pH-7.5, 1mM EDTA and 20% Glycerol.
Physical Appearance : Sterile Filtered clear solution.
Storage : Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
Pathways : Cell adhesion molecules (CAMs); Signaling in Immune system
Gene Name : PDCD1LG2 programmed cell death 1 ligand 2 [ Homo sapiens ]
Official Symbol : PDCD1LG2
Synonyms : PDCD1LG2; programmed cell death 1 ligand 2; B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; MGC142238; MGC142240; bA574F11.2; PD-1-ligand 2; programmed death ligand 2
Gene ID : 80380
mRNA Refseq : NM_025239
Protein Refseq : NP_079515
MIM : 605723
UniProt ID : Q9BQ51
Chromosome Location : 9p24.2
Function : molecular_function; protein binding; receptor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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